Gusb protein (Rattus norvegicus) - STRING interaction network

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Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gba3	Glb1	ENSRNOP00000069571	ENSRNOP00000013632	Glucosylceramidase beta 3; Belongs to the glycosyl hydrolase 1 family.	Beta-galactosidase.	0.737
Gba3	Gusb	ENSRNOP00000069571	ENSRNOP00000045033	Glucosylceramidase beta 3; Belongs to the glycosyl hydrolase 1 family.	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.916
Gba3	RGD1559459	ENSRNOP00000069571	ENSRNOP00000058927	Glucosylceramidase beta 3; Belongs to the glycosyl hydrolase 1 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.511
Gba3	Ugt1a1	ENSRNOP00000069571	ENSRNOP00000025045	Glucosylceramidase beta 3; Belongs to the glycosyl hydrolase 1 family.	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Glucuronates opioids and bilirubin; Belongs to the UDP-glycosyltransferase family.	0.417
Gba3	Ugt2b1	ENSRNOP00000069571	ENSRNOP00000002724	Glucosylceramidase beta 3; Belongs to the glycosyl hydrolase 1 family.	UDP-glucuronosyltransferase 2B1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds; Belongs to the UDP-glycosyltransferase family.	0.443
Glb1	Gba3	ENSRNOP00000013632	ENSRNOP00000069571	Beta-galactosidase.	Glucosylceramidase beta 3; Belongs to the glycosyl hydrolase 1 family.	0.737
Glb1	Gusb	ENSRNOP00000013632	ENSRNOP00000045033	Beta-galactosidase.	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.915
Glb1	Hyal4	ENSRNOP00000013632	ENSRNOP00000072978	Beta-galactosidase.	Hyaluronidase.	0.472
Glb1	Hyal5	ENSRNOP00000013632	ENSRNOP00000057222	Beta-galactosidase.	Hyaluronidase.	0.470
Glb1	Kl	ENSRNOP00000013632	ENSRNOP00000001449	Beta-galactosidase.	Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).	0.831
Gusb	Gba3	ENSRNOP00000045033	ENSRNOP00000069571	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Glucosylceramidase beta 3; Belongs to the glycosyl hydrolase 1 family.	0.916
Gusb	Glb1	ENSRNOP00000045033	ENSRNOP00000013632	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Beta-galactosidase.	0.915
Gusb	Hyal1	ENSRNOP00000045033	ENSRNOP00000021408	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Hyaluronidase-1; May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.	0.941
Gusb	Hyal2	ENSRNOP00000045033	ENSRNOP00000075204	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Hyaluronidase-2; Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R (By similarity); Belongs to the glycosyl hydrolase 56 family.	0.932
Gusb	Hyal4	ENSRNOP00000045033	ENSRNOP00000072978	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Hyaluronidase.	0.927
Gusb	Hyal5	ENSRNOP00000045033	ENSRNOP00000057222	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Hyaluronidase.	0.926
Gusb	Kl	ENSRNOP00000045033	ENSRNOP00000001449	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).	0.945
Gusb	RGD1559459	ENSRNOP00000045033	ENSRNOP00000058927	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.937
Gusb	Ugt1a1	ENSRNOP00000045033	ENSRNOP00000025045	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Glucuronates opioids and bilirubin; Belongs to the UDP-glycosyltransferase family.	0.944
Gusb	Ugt2b1	ENSRNOP00000045033	ENSRNOP00000002724	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	UDP-glucuronosyltransferase 2B1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds; Belongs to the UDP-glycosyltransferase family.	0.927

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