node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gusb | Hyal5 | ENSRNOP00000045033 | ENSRNOP00000057222 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | Hyaluronidase. | 0.945 |
Gusb | Hyal6 | ENSRNOP00000045033 | ENSRNOP00000009405 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | Hyaluronidase. | 0.945 |
Gusb | Kl | ENSRNOP00000045033 | ENSRNOP00000001449 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). | 0.953 |
Gusb | LOC100909505 | ENSRNOP00000045033 | ENSRNOP00000006566 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.955 |
Gusb | RGD1559459 | ENSRNOP00000045033 | ENSRNOP00000058927 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.960 |
Gusb | Ugt1a1 | ENSRNOP00000045033 | ENSRNOP00000025045 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Glucuronates opioids and bilirubin; Belongs to the UDP-glycosyltransferase family. | 0.957 |
Gusb | Ugt2a1 | ENSRNOP00000045033 | ENSRNOP00000002705 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.963 |
Gusb | Ugt2b | ENSRNOP00000045033 | ENSRNOP00000045002 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | UDP-glucuronosyltransferase 2B37; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. 2B37 is about 30-fold less active than 2B5 toward testosterone and dihydrotestosterone; Belongs to the UDP-glycosyltransferase family. | 0.957 |
Gusb | Ugt2b1 | ENSRNOP00000045033 | ENSRNOP00000002724 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | UDP-glucuronosyltransferase 2B1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds; Belongs to the UDP-glycosyltransferase family. | 0.952 |
Gusb | Ugt2b35 | ENSRNOP00000045033 | ENSRNOP00000002712 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | UDP-glucuronosyltransferase 2B15; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Catalyzes the transfer of glucuronic acid from UDP- glucuronic acid to various aglycone molecules. Catalyzes the glucuronidation of monoterpenoid alcohols, such as (-)-borneol, (+)- menthol, and (-)- nopol. In addition, a number of simple phenolic compounds, such as hydroxybiphenyls, 7-hydroxylated coumarins, p- nitrophenol, and food-derived substances (e.g. naringenin and eugenol), and 4-methylumbelliferone are also sub [...] | 0.952 |
Hyal5 | Gusb | ENSRNOP00000057222 | ENSRNOP00000045033 | Hyaluronidase. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | 0.945 |
Hyal6 | Gusb | ENSRNOP00000009405 | ENSRNOP00000045033 | Hyaluronidase. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | 0.945 |
Kl | Gusb | ENSRNOP00000001449 | ENSRNOP00000045033 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | 0.953 |
Kl | RGD1559459 | ENSRNOP00000001449 | ENSRNOP00000058927 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.903 |
Kl | Ugt1a1 | ENSRNOP00000001449 | ENSRNOP00000025045 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). | UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Glucuronates opioids and bilirubin; Belongs to the UDP-glycosyltransferase family. | 0.908 |
Kl | Ugt2a1 | ENSRNOP00000001449 | ENSRNOP00000002705 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.908 |
Kl | Ugt2b | ENSRNOP00000001449 | ENSRNOP00000045002 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). | UDP-glucuronosyltransferase 2B37; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. 2B37 is about 30-fold less active than 2B5 toward testosterone and dihydrotestosterone; Belongs to the UDP-glycosyltransferase family. | 0.903 |
Kl | Ugt2b1 | ENSRNOP00000001449 | ENSRNOP00000002724 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). | UDP-glucuronosyltransferase 2B1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds; Belongs to the UDP-glycosyltransferase family. | 0.903 |
Kl | Ugt2b35 | ENSRNOP00000001449 | ENSRNOP00000002712 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). | UDP-glucuronosyltransferase 2B15; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Catalyzes the transfer of glucuronic acid from UDP- glucuronic acid to various aglycone molecules. Catalyzes the glucuronidation of monoterpenoid alcohols, such as (-)-borneol, (+)- menthol, and (-)- nopol. In addition, a number of simple phenolic compounds, such as hydroxybiphenyls, 7-hydroxylated coumarins, p- nitrophenol, and food-derived substances (e.g. naringenin and eugenol), and 4-methylumbelliferone are also sub [...] | 0.904 |
LOC100909505 | Gusb | ENSRNOP00000006566 | ENSRNOP00000045033 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | 0.955 |