STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ces5aCarboxylesterase 5A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. (547 aa)    
Predicted Functional Partners:
LOC259246
15.5 kDa fatty acid-binding protein; Major urinary proteins (Mups) bind and release pheromones. They may also protect pheromones from oxidation. In this context, they play a role in the regulation of social behaviors, such as aggression, mating, pup-suckling, territory establishment and dominance. Acts as a kairomone, detected by the prey vomeronasal organ and inducing fear reactions in mice; Belongs to the calycin superfamily. Lipocalin family.
   
 
 0.619
Sult6b1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.494
Spint5p
Serine peptidase inhibitor, Kunitz type 5.
   
  
 0.472
D4A0Q5_RAT
BPTI/Kunitz inhibitor domain-containing protein.
   
  
 0.444
LOC103690354
Ribonuclease pancreatic beta-type; Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double- stranded RNA (By similarity); Belongs to the pancreatic ribonuclease family.
   
  
 0.413
Rnase1
Ribonuclease pancreatic beta-type; Belongs to the pancreatic ribonuclease family.
   
  
 0.413
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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