Impg2 protein (Rattus norvegicus) - STRING interaction network

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Impg2

Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin. (1241 aa)

Predicted Functional Partners:

Ubac1

0.605

Pde6g

0.571

Pcare

0.565

Gnat3

0.539

Zfp513

0.528

Sla2

0.523

Prcd

0.513

Lrriq1

0.510

Pde6a

0.482

Ttc8

0.477

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gnat3	Impg2	ENSRNOP00000007032	ENSRNOP00000046981	Guanine nucleotide-binding protein G(t) subunit alpha-3; Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP- phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultim [...]	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	0.539
Gnat3	Pde6a	ENSRNOP00000007032	ENSRNOP00000024171	Guanine nucleotide-binding protein G(t) subunit alpha-3; Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP- phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultim [...]	Phosphodiesterase.	0.635
Gnat3	Pde6g	ENSRNOP00000007032	ENSRNOP00000064365	Guanine nucleotide-binding protein G(t) subunit alpha-3; Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP- phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultim [...]	RCG33796, isoform CRA_b.	0.838
Gnat3	Ubac1	ENSRNOP00000007032	ENSRNOP00000024352	Guanine nucleotide-binding protein G(t) subunit alpha-3; Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP- phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultim [...]	Ubiquitin-associated domain-containing protein 1; Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle (By similarity).	0.401
Impg2	Gnat3	ENSRNOP00000046981	ENSRNOP00000007032	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	Guanine nucleotide-binding protein G(t) subunit alpha-3; Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP- phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultim [...]	0.539
Impg2	Lrriq1	ENSRNOP00000046981	ENSRNOP00000067860	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	Leucine-rich repeats and IQ motif-containing 1.	0.510
Impg2	Pcare	ENSRNOP00000046981	ENSRNOP00000011832	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	Photoreceptor cilium actin regulator.	0.565
Impg2	Pde6a	ENSRNOP00000046981	ENSRNOP00000024171	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	Phosphodiesterase.	0.482
Impg2	Pde6g	ENSRNOP00000046981	ENSRNOP00000064365	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	RCG33796, isoform CRA_b.	0.571
Impg2	Prcd	ENSRNOP00000046981	ENSRNOP00000058855	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	Uncharacterized protein.	0.513
Impg2	Sla2	ENSRNOP00000046981	ENSRNOP00000027581	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	Similar to Src-like adaptor protein-2 (Predicted).	0.523
Impg2	Ttc8	ENSRNOP00000046981	ENSRNOP00000068618	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	Tetratricopeptide repeat domain 8.	0.477
Impg2	Ubac1	ENSRNOP00000046981	ENSRNOP00000024352	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	Ubiquitin-associated domain-containing protein 1; Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle (By similarity).	0.605
Impg2	Zfp513	ENSRNOP00000046981	ENSRNOP00000040002	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	Zinc finger protein 513; Transcriptional regulator that plays a role in retinal development and maintenance.	0.528
Lrriq1	Impg2	ENSRNOP00000067860	ENSRNOP00000046981	Leucine-rich repeats and IQ motif-containing 1.	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	0.510
Pcare	Impg2	ENSRNOP00000011832	ENSRNOP00000046981	Photoreceptor cilium actin regulator.	Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.	0.565
Pcare	Pde6a	ENSRNOP00000011832	ENSRNOP00000024171	Photoreceptor cilium actin regulator.	Phosphodiesterase.	0.521
Pcare	Pde6g	ENSRNOP00000011832	ENSRNOP00000064365	Photoreceptor cilium actin regulator.	RCG33796, isoform CRA_b.	0.544
Pcare	Prcd	ENSRNOP00000011832	ENSRNOP00000058855	Photoreceptor cilium actin regulator.	Uncharacterized protein.	0.569
Pcare	Ttc8	ENSRNOP00000011832	ENSRNOP00000068618	Photoreceptor cilium actin regulator.	Tetratricopeptide repeat domain 8.	0.473

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