Layn protein (Rattus norvegicus) - STRING interaction network

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Score

Layn

Layilin. (376 aa)

Predicted Functional Partners:

Tln1

0.849

Tln2

0.708

Lyve1

0.578

Ccdc102a

0.565

Tigit

0.520

Mageh1

0.515

Tlnrd1

0.504

Hmmr

0.458

Parvg

0.452

Lag3

0.448

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccdc102a	Layn	ENSRNOP00000035778	ENSRNOP00000050686	Coiled-coil domain-containing 102A.	Layilin.	0.565
Hmmr	Layn	ENSRNOP00000070444	ENSRNOP00000050686	Hyaluronan-mediated motility receptor; Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity (By similarity). May act as a regulator of adipogenisis (By similarity).	Layilin.	0.458
Hmmr	Lyve1	ENSRNOP00000070444	ENSRNOP00000036731	Hyaluronan-mediated motility receptor; Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity (By similarity). May act as a regulator of adipogenisis (By similarity).	Extracellular link domain-containing 1 (Predicted).	0.497
Lag3	Layn	ENSRNOP00000036771	ENSRNOP00000050686	Secreted lymphocyte activation gene 3 protein; Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells. Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell inhibitory function. Following TCR engagement, LAG3 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation. May inhibit antigen-specific T-cell activation in synergy with PDCD1/PD-1, possibly by acting as a coreceptor for PDCD1/PD-1. Negatively regulates the proliferation, act [...]	Layilin.	0.448
Lag3	Tigit	ENSRNOP00000036771	ENSRNOP00000074881	Secreted lymphocyte activation gene 3 protein; Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells. Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell inhibitory function. Following TCR engagement, LAG3 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation. May inhibit antigen-specific T-cell activation in synergy with PDCD1/PD-1, possibly by acting as a coreceptor for PDCD1/PD-1. Negatively regulates the proliferation, act [...]	T cell immunoreceptor with Ig and ITIM domains.	0.914
Layn	Ccdc102a	ENSRNOP00000050686	ENSRNOP00000035778	Layilin.	Coiled-coil domain-containing 102A.	0.565
Layn	Hmmr	ENSRNOP00000050686	ENSRNOP00000070444	Layilin.	Hyaluronan-mediated motility receptor; Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity (By similarity). May act as a regulator of adipogenisis (By similarity).	0.458
Layn	Lag3	ENSRNOP00000050686	ENSRNOP00000036771	Layilin.	Secreted lymphocyte activation gene 3 protein; Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells. Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell inhibitory function. Following TCR engagement, LAG3 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation. May inhibit antigen-specific T-cell activation in synergy with PDCD1/PD-1, possibly by acting as a coreceptor for PDCD1/PD-1. Negatively regulates the proliferation, act [...]	0.448
Layn	Lyve1	ENSRNOP00000050686	ENSRNOP00000036731	Layilin.	Extracellular link domain-containing 1 (Predicted).	0.578
Layn	Mageh1	ENSRNOP00000050686	ENSRNOP00000004238	Layilin.	Melanoma-associated antigen H1.	0.515
Layn	Parvg	ENSRNOP00000050686	ENSRNOP00000070638	Layilin.	Parvin, gamma.	0.452
Layn	Tigit	ENSRNOP00000050686	ENSRNOP00000074881	Layilin.	T cell immunoreceptor with Ig and ITIM domains.	0.520
Layn	Tln1	ENSRNOP00000050686	ENSRNOP00000022401	Layilin.	RCG55135, isoform CRA_b.	0.849
Layn	Tln2	ENSRNOP00000050686	ENSRNOP00000024885	Layilin.	Talin 2.	0.708
Layn	Tlnrd1	ENSRNOP00000050686	ENSRNOP00000016455	Layilin.	Mesoderm development candidate 1.	0.504
Lyve1	Hmmr	ENSRNOP00000036731	ENSRNOP00000070444	Extracellular link domain-containing 1 (Predicted).	Hyaluronan-mediated motility receptor; Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity (By similarity). May act as a regulator of adipogenisis (By similarity).	0.497
Lyve1	Layn	ENSRNOP00000036731	ENSRNOP00000050686	Extracellular link domain-containing 1 (Predicted).	Layilin.	0.578
Mageh1	Layn	ENSRNOP00000004238	ENSRNOP00000050686	Melanoma-associated antigen H1.	Layilin.	0.515
Parvg	Layn	ENSRNOP00000070638	ENSRNOP00000050686	Parvin, gamma.	Layilin.	0.452
Parvg	Tln1	ENSRNOP00000070638	ENSRNOP00000022401	Parvin, gamma.	RCG55135, isoform CRA_b.	0.656

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