STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Cpped1Serine/threonine-protein phosphatase CPPED1; Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes (By similarity). (312 aa)    
Predicted Functional Partners:
Pudp
Haloacid dehalogenase-like hydrolase domain containing 1A (Predicted).
  
  
 0.741
Pnpla4
Patatin-like phospholipase domain-containing 4.
      
 0.713
Lipt1
Lipoyltransferase 1.
     
 0.660
Nudt12
Nudix (Nucleoside diphosphate linked moiety X)-type motif 12 (Predicted).
  
 0.652
Drc7
Dynein regulatory complex subunit 7.
      
 0.596
Ipp
Intracisternal A particle-promoted polypeptide.
   
 
 0.573
Txndc11
Thioredoxin domain-containing 11.
   
  
 0.553
Klhl2
Kelch-like protein 2; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation. Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4 (By similarity). Promotes growth of cell projections in oligodendrocyte precursors. Plays a role in the reorganization of the actin cytoskeleton.
   
 
 0.549
Nadk
NAD kinase.
  
 
  0.539
Sbsn
Suprabasin.
      
 0.539
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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