node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccr7 | Cd19 | ENSRNOP00000014163 | ENSRNOP00000051906 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | CD19 molecule. | 0.821 |
Ccr7 | Cd1d1 | ENSRNOP00000014163 | ENSRNOP00000022150 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | Antigen-presenting glycoprotein CD1d; Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T- cells. | 0.537 |
Ccr7 | Cd2 | ENSRNOP00000014163 | ENSRNOP00000021268 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | 0.535 |
Ccr7 | Cd3e | ENSRNOP00000014163 | ENSRNOP00000047591 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | CD3 antigen, epsilon polypeptide (Predicted). | 0.716 |
Ccr7 | Cd4 | ENSRNOP00000014163 | ENSRNOP00000021915 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.934 |
Ccr7 | Cd5 | ENSRNOP00000014163 | ENSRNOP00000070123 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | T-cell surface glycoprotein CD5; May act as a receptor in regulating T-cell proliferation. | 0.855 |
Ccr7 | Cr2 | ENSRNOP00000014163 | ENSRNOP00000073714 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | Complement C3d receptor 2. | 0.610 |
Ccr7 | Lck | ENSRNOP00000014163 | ENSRNOP00000012936 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | Proto-oncogene tyrosine-protein kinase LCK; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associa [...] | 0.445 |
Ccr7 | Spn | ENSRNOP00000014163 | ENSRNOP00000051894 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | CD43 cytoplasmic tail; Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration. Positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN). Negatively regulates Th2 cell differentiation and predisposes the differentiation of T-cells towards a Th1 lineage commitment. Promotes the expression of IFN-gamma by T- cells during T-cell receptor (TCR) activation of naive cells and induces the expression of IFN-gamma by [...] | 0.538 |
Cd19 | Ccr7 | ENSRNOP00000051906 | ENSRNOP00000014163 | CD19 molecule. | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | 0.821 |
Cd19 | Cd1d1 | ENSRNOP00000051906 | ENSRNOP00000022150 | CD19 molecule. | Antigen-presenting glycoprotein CD1d; Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T- cells. | 0.742 |
Cd19 | Cd2 | ENSRNOP00000051906 | ENSRNOP00000021268 | CD19 molecule. | T-cell surface antigen CD2; CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. | 0.792 |
Cd19 | Cd3e | ENSRNOP00000051906 | ENSRNOP00000047591 | CD19 molecule. | CD3 antigen, epsilon polypeptide (Predicted). | 0.904 |
Cd19 | Cd4 | ENSRNOP00000051906 | ENSRNOP00000021915 | CD19 molecule. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.979 |
Cd19 | Cd5 | ENSRNOP00000051906 | ENSRNOP00000070123 | CD19 molecule. | T-cell surface glycoprotein CD5; May act as a receptor in regulating T-cell proliferation. | 0.970 |
Cd19 | Cd72 | ENSRNOP00000051906 | ENSRNOP00000057186 | CD19 molecule. | Cd72 molecule. | 0.617 |
Cd19 | Cr2 | ENSRNOP00000051906 | ENSRNOP00000073714 | CD19 molecule. | Complement C3d receptor 2. | 0.999 |
Cd19 | Lck | ENSRNOP00000051906 | ENSRNOP00000012936 | CD19 molecule. | Proto-oncogene tyrosine-protein kinase LCK; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associa [...] | 0.667 |
Cd19 | Spn | ENSRNOP00000051906 | ENSRNOP00000051894 | CD19 molecule. | CD43 cytoplasmic tail; Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration. Positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN). Negatively regulates Th2 cell differentiation and predisposes the differentiation of T-cells towards a Th1 lineage commitment. Promotes the expression of IFN-gamma by T- cells during T-cell receptor (TCR) activation of naive cells and induces the expression of IFN-gamma by [...] | 0.927 |
Cd1d1 | Ccr7 | ENSRNOP00000022150 | ENSRNOP00000014163 | Antigen-presenting glycoprotein CD1d; Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T- cells. | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | 0.537 |