node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Agxt | Asns | ENSRNOP00000030340 | ENSRNOP00000010079 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Asparagine synthetase [glutamine-hydrolyzing]. | 0.721 |
Agxt | Gldc | ENSRNOP00000030340 | ENSRNOP00000069291 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.722 |
Agxt | Phgdh | ENSRNOP00000030340 | ENSRNOP00000053019 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Does not catalyze the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate. | 0.784 |
Agxt | Psat1 | ENSRNOP00000030340 | ENSRNOP00000074840 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Phosphoserine aminotransferase. | 0.555 |
Agxt | Psph | ENSRNOP00000030340 | ENSRNOP00000001228 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Phosphoserine phosphatase; Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates (By similarity); Belongs to the HAD-like hydrolase superfamily. SerB family. | 0.989 |
Agxt | Shmt1 | ENSRNOP00000030340 | ENSRNOP00000007092 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.984 |
Agxt | Shmt2 | ENSRNOP00000030340 | ENSRNOP00000011082 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.980 |
Asns | Agxt | ENSRNOP00000010079 | ENSRNOP00000030340 | Asparagine synthetase [glutamine-hydrolyzing]. | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 0.721 |
Asns | Mthfd2 | ENSRNOP00000010079 | ENSRNOP00000014603 | Asparagine synthetase [glutamine-hydrolyzing]. | RCG56426. | 0.714 |
Asns | Phgdh | ENSRNOP00000010079 | ENSRNOP00000053019 | Asparagine synthetase [glutamine-hydrolyzing]. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Does not catalyze the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate. | 0.851 |
Asns | Psat1 | ENSRNOP00000010079 | ENSRNOP00000074840 | Asparagine synthetase [glutamine-hydrolyzing]. | Phosphoserine aminotransferase. | 0.860 |
Asns | Psph | ENSRNOP00000010079 | ENSRNOP00000001228 | Asparagine synthetase [glutamine-hydrolyzing]. | Phosphoserine phosphatase; Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates (By similarity); Belongs to the HAD-like hydrolase superfamily. SerB family. | 0.686 |
Asns | Shmt1 | ENSRNOP00000010079 | ENSRNOP00000007092 | Asparagine synthetase [glutamine-hydrolyzing]. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.552 |
Asns | Shmt2 | ENSRNOP00000010079 | ENSRNOP00000011082 | Asparagine synthetase [glutamine-hydrolyzing]. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.614 |
Gldc | Agxt | ENSRNOP00000069291 | ENSRNOP00000030340 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 0.722 |
Gldc | Mthfd2 | ENSRNOP00000069291 | ENSRNOP00000014603 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | RCG56426. | 0.917 |
Gldc | Phgdh | ENSRNOP00000069291 | ENSRNOP00000053019 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Does not catalyze the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate. | 0.793 |
Gldc | Psat1 | ENSRNOP00000069291 | ENSRNOP00000074840 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Phosphoserine aminotransferase. | 0.684 |
Gldc | Psph | ENSRNOP00000069291 | ENSRNOP00000001228 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Phosphoserine phosphatase; Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates (By similarity); Belongs to the HAD-like hydrolase superfamily. SerB family. | 0.640 |
Gldc | Shmt1 | ENSRNOP00000069291 | ENSRNOP00000007092 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.969 |