node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Il17a | Il17b | ENSRNOP00000016664 | ENSRNOP00000026679 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Interleukin 17B, isoform CRA_a. | 0.683 |
Il17a | Il17d | ENSRNOP00000016664 | ENSRNOP00000074427 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Interleukin 17D. | 0.640 |
Il17a | Il17f | ENSRNOP00000016664 | ENSRNOP00000016717 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Interleukin-17F; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover. Also involved in stimulating proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis. Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation. | 0.935 |
Il17a | Il17ra | ENSRNOP00000016664 | ENSRNOP00000014885 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Interleukin 17 receptor A. | 0.999 |
Il17a | Il17rb | ENSRNOP00000016664 | ENSRNOP00000065845 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Interleukin 17 receptor B (Predicted), isoform CRA_b. | 0.793 |
Il17a | Il17rc | ENSRNOP00000016664 | ENSRNOP00000037747 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Interleukin 17 receptor C. | 0.999 |
Il17a | Il17rd | ENSRNOP00000016664 | ENSRNOP00000031556 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Interleukin 17 receptor D. | 0.824 |
Il17a | Il17re | ENSRNOP00000016664 | ENSRNOP00000053347 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Interleukin-17 receptor E; Specific functional receptor for IL17C, signaling through the NF-kappa-B and MAPK pathways. Requires TRAF3IP2 /ACT1 for signaling. Crucial regulator in innate immunity to bacterial pathogens (By similarity). | 0.747 |
Il17a | Il25 | ENSRNOP00000016664 | ENSRNOP00000022563 | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | Interleukin 25. | 0.743 |
Il17b | Il17a | ENSRNOP00000026679 | ENSRNOP00000016664 | Interleukin 17B, isoform CRA_a. | Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines. | 0.683 |
Il17b | Il17d | ENSRNOP00000026679 | ENSRNOP00000074427 | Interleukin 17B, isoform CRA_a. | Interleukin 17D. | 0.489 |
Il17b | Il17f | ENSRNOP00000026679 | ENSRNOP00000016717 | Interleukin 17B, isoform CRA_a. | Interleukin-17F; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover. Also involved in stimulating proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis. Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation. | 0.554 |
Il17b | Il17ra | ENSRNOP00000026679 | ENSRNOP00000014885 | Interleukin 17B, isoform CRA_a. | Interleukin 17 receptor A. | 0.759 |
Il17b | Il17rb | ENSRNOP00000026679 | ENSRNOP00000065845 | Interleukin 17B, isoform CRA_a. | Interleukin 17 receptor B (Predicted), isoform CRA_b. | 0.995 |
Il17b | Il17rc | ENSRNOP00000026679 | ENSRNOP00000037747 | Interleukin 17B, isoform CRA_a. | Interleukin 17 receptor C. | 0.737 |
Il17b | Il17rd | ENSRNOP00000026679 | ENSRNOP00000031556 | Interleukin 17B, isoform CRA_a. | Interleukin 17 receptor D. | 0.736 |
Il17b | Il17re | ENSRNOP00000026679 | ENSRNOP00000053347 | Interleukin 17B, isoform CRA_a. | Interleukin-17 receptor E; Specific functional receptor for IL17C, signaling through the NF-kappa-B and MAPK pathways. Requires TRAF3IP2 /ACT1 for signaling. Crucial regulator in innate immunity to bacterial pathogens (By similarity). | 0.799 |
Il17b | Il25 | ENSRNOP00000026679 | ENSRNOP00000022563 | Interleukin 17B, isoform CRA_a. | Interleukin 25. | 0.586 |
Il17c | Il17d | ENSRNOP00000017358 | ENSRNOP00000074427 | Interleukin 17C. | Interleukin 17D. | 0.448 |
Il17c | Il17ra | ENSRNOP00000017358 | ENSRNOP00000014885 | Interleukin 17C. | Interleukin 17 receptor A. | 0.839 |