node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arhgap1 | Retreg2 | ENSRNOP00000059324 | ENSRNOP00000054145 | Rho GTPase-activating protein 1. | Reticulophagy regulator 2. | 0.627 |
Eif6 | Gnl1 | ENSRNOP00000071658 | ENSRNOP00000045697 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster; Belongs to the TRAFAC class YlqF/YawG GTPase family. | 0.868 |
Eif6 | Gnl2 | ENSRNOP00000071658 | ENSRNOP00000012702 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. | 0.973 |
Eif6 | Lsg1 | ENSRNOP00000071658 | ENSRNOP00000074962 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Large subunit GTPase 1 homolog; GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (By similarity). | 0.972 |
Eif6 | Nmd3 | ENSRNOP00000071658 | ENSRNOP00000063236 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.978 |
Eif6 | Pa2g4 | ENSRNOP00000071658 | ENSRNOP00000006578 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Proliferation-associated protein 2G4; May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1- regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved [...] | 0.882 |
Eif6 | Q7TP85_RAT | ENSRNOP00000071658 | ENSRNOP00000034774 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Ab1-334. | 0.874 |
Eif6 | Retreg2 | ENSRNOP00000071658 | ENSRNOP00000054145 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Reticulophagy regulator 2. | 0.705 |
Eif6 | Rsl24d1 | ENSRNOP00000071658 | ENSRNOP00000068858 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity). | 0.976 |
Gabarap | Retreg2 | ENSRNOP00000023724 | ENSRNOP00000054145 | Gamma-aminobutyric acid receptor-associated protein; Involved in apoptosis (By similarity). May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in autophagy (By similarity). | Reticulophagy regulator 2. | 0.727 |
Gnl1 | Eif6 | ENSRNOP00000045697 | ENSRNOP00000071658 | Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster; Belongs to the TRAFAC class YlqF/YawG GTPase family. | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 0.868 |
Gnl1 | Gnl2 | ENSRNOP00000045697 | ENSRNOP00000012702 | Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster; Belongs to the TRAFAC class YlqF/YawG GTPase family. | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. | 0.727 |
Gnl1 | Nmd3 | ENSRNOP00000045697 | ENSRNOP00000063236 | Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster; Belongs to the TRAFAC class YlqF/YawG GTPase family. | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.935 |
Gnl1 | Pa2g4 | ENSRNOP00000045697 | ENSRNOP00000006578 | Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster; Belongs to the TRAFAC class YlqF/YawG GTPase family. | Proliferation-associated protein 2G4; May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1- regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved [...] | 0.836 |
Gnl1 | Q7TP85_RAT | ENSRNOP00000045697 | ENSRNOP00000034774 | Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster; Belongs to the TRAFAC class YlqF/YawG GTPase family. | Ab1-334. | 0.832 |
Gnl1 | Retreg2 | ENSRNOP00000045697 | ENSRNOP00000054145 | Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster; Belongs to the TRAFAC class YlqF/YawG GTPase family. | Reticulophagy regulator 2. | 0.695 |
Gnl1 | Rsl24d1 | ENSRNOP00000045697 | ENSRNOP00000068858 | Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster; Belongs to the TRAFAC class YlqF/YawG GTPase family. | Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity). | 0.856 |
Gnl2 | Eif6 | ENSRNOP00000012702 | ENSRNOP00000071658 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 0.973 |
Gnl2 | Gnl1 | ENSRNOP00000012702 | ENSRNOP00000045697 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. | Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster; Belongs to the TRAFAC class YlqF/YawG GTPase family. | 0.727 |
Gnl2 | Lsg1 | ENSRNOP00000012702 | ENSRNOP00000074962 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. | Large subunit GTPase 1 homolog; GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (By similarity). | 0.891 |