Oxgr1 protein (Rattus norvegicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Oxgr1

2-oxoglutarate receptor 1; Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity). (337 aa)

Predicted Functional Partners:

Ltc4s

0.617

Aldh18a1

0.540

Aldh18a1-2

0.540

Slc26a4

0.473

Slc13a2

0.450

Cysltr1

0.432

Gpsm3

0.400

Pcp2

0.400

Gpsm1

0.400

Gpsm2

0.400

Your Current Organism:

Rattus norvegicus

NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aldh18a1	Aldh18a1-2	ENSRNOP00000020940	ENSRNOP00000074318	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Aldehyde dehydrogenase 18 family, member A1.	0.999
Aldh18a1	Gpsm1	ENSRNOP00000020940	ENSRNOP00000062075	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein- coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.	0.471
Aldh18a1	Gpsm2	ENSRNOP00000020940	ENSRNOP00000062330	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	G-protein-signaling modulator 2.	0.469
Aldh18a1	Oxgr1	ENSRNOP00000020940	ENSRNOP00000054374	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	2-oxoglutarate receptor 1; Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity).	0.540
Aldh18a1	Pcp2	ENSRNOP00000020940	ENSRNOP00000001313	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Purkinje cell protein 2 (L7), isoform CRA_c.	0.469
Aldh18a1-2	Aldh18a1	ENSRNOP00000074318	ENSRNOP00000020940	Aldehyde dehydrogenase 18 family, member A1.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.999
Aldh18a1-2	Gpsm1	ENSRNOP00000074318	ENSRNOP00000062075	Aldehyde dehydrogenase 18 family, member A1.	G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein- coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.	0.469
Aldh18a1-2	Gpsm2	ENSRNOP00000074318	ENSRNOP00000062330	Aldehyde dehydrogenase 18 family, member A1.	G-protein-signaling modulator 2.	0.469
Aldh18a1-2	Oxgr1	ENSRNOP00000074318	ENSRNOP00000054374	Aldehyde dehydrogenase 18 family, member A1.	2-oxoglutarate receptor 1; Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity).	0.540
Aldh18a1-2	Pcp2	ENSRNOP00000074318	ENSRNOP00000001313	Aldehyde dehydrogenase 18 family, member A1.	Purkinje cell protein 2 (L7), isoform CRA_c.	0.469
Cysltr1	Ltc4s	ENSRNOP00000075854	ENSRNOP00000004359	Cysteinyl leukotriene receptor 1; Receptor for cysteinyl leukotrienes mediating constriction of the microvascular smooth muscle during an inflammatory response. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity).	Leukotriene C4 synthase; Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4.	0.820
Cysltr1	Oxgr1	ENSRNOP00000075854	ENSRNOP00000054374	Cysteinyl leukotriene receptor 1; Receptor for cysteinyl leukotrienes mediating constriction of the microvascular smooth muscle during an inflammatory response. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity).	2-oxoglutarate receptor 1; Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity).	0.432
Gpsm1	Aldh18a1	ENSRNOP00000062075	ENSRNOP00000020940	G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein- coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.471
Gpsm1	Aldh18a1-2	ENSRNOP00000062075	ENSRNOP00000074318	G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein- coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.	Aldehyde dehydrogenase 18 family, member A1.	0.469
Gpsm1	Gpsm3	ENSRNOP00000062075	ENSRNOP00000000510	G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein- coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.	G-protein-signaling modulator 3; Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.	0.711
Gpsm1	Oxgr1	ENSRNOP00000062075	ENSRNOP00000054374	G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein- coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.	2-oxoglutarate receptor 1; Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity).	0.400
Gpsm2	Aldh18a1	ENSRNOP00000062330	ENSRNOP00000020940	G-protein-signaling modulator 2.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.469
Gpsm2	Aldh18a1-2	ENSRNOP00000062330	ENSRNOP00000074318	G-protein-signaling modulator 2.	Aldehyde dehydrogenase 18 family, member A1.	0.469
Gpsm2	Gpsm3	ENSRNOP00000062330	ENSRNOP00000000510	G-protein-signaling modulator 2.	G-protein-signaling modulator 3; Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.	0.697
Gpsm2	Oxgr1	ENSRNOP00000062330	ENSRNOP00000054374	G-protein-signaling modulator 2.	2-oxoglutarate receptor 1; Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity).	0.400

page 1 of 3

Server load: low (38%) [HD]

Permalink

Network

Neighborhood

Databases

Cooccurrence

Textmining

Coexpression

Experiments

Fusion

© STRING Consortium 2025

Credits

Access

Info

About