STRINGSTRING
Gpx6 protein (Rattus norvegicus) - STRING interaction network
"Gpx6" - Glutathione peroxidase 6 in Rattus norvegicus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gpx6Glutathione peroxidase 6 (220 aa)    
Predicted Functional Partners:
Gss
Glutathione synthetase (474 aa)
         
  0.941
Gstt2
Glutathione S-transferase theta-2 ; Catalyzes the inactivation of reactive sulfate esters in carcinogenic arylmethanols. Highest activity towards ethacrynic acid and cumene hydroperoxide (244 aa)
     
 
  0.940
Gstt1
Glutathione S-transferase theta-1 ; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity (240 aa)
     
 
  0.938
Gstk1
Glutathione S-transferase kappa 1 ; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment (226 aa)
         
  0.919
Hpgds
Hematopoietic prostaglandin D synthase ; Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide (199 aa)
     
 
  0.918
Gsta2
Glutathione S-transferase alpha-1 ; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (222 aa)
     
 
  0.916
Ggt1
Gamma-glutamyltransferase 1 (441 aa)
     
 
  0.915
Ggt6
Gamma-glutamyltransferase 6 Gamma-glutamyltransferase 6 heavy chain Gamma-glutamyltransferase 6 light chain; Cleaves glutathione conjugates (498 aa)
     
 
  0.915
Ggt7
Gamma-glutamyltransferase 7 Gamma-glutamyltransferase 7 heavy chain Gamma-glutamyltransferase 7 light chain; Cleaves glutathione conjugates (662 aa)
     
 
  0.915
Gstyc2
Glutathione S-transferase alpha-5 ; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide (221 aa)
     
 
  0.912
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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