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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lgals12Galectin. (314 aa)    
Predicted Functional Partners:
A0A0G2JUH9_RAT
SKICH domain-containing protein.
    
 
 0.786
Ankef1
Ankyrin repeat and EF-hand domain-containing 1.
   
  
 0.626
Mindy3
Similar to RIKEN cDNA 2310047O13 (Predicted).
      
 0.584
Lgals2
Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known.
      
 0.538
Timp4
Metalloproteinase inhibitor 4; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
   
  
 0.537
Vps13c
Vacuolar protein sorting 13 homolog C.
   
 
 0.495
Vps13a
Vacuolar protein sorting 13 homolog A.
   
 
 0.469
Siglec5
Sialic acid-binding Ig-like lectin 5.
  
 
 0.450
Vstm4
V-set and transmembrane domain-containing 4.
   
 
 0.448
Hcfc1r1
Host cell factor C1 regulator 1; Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus (By similarity).
   
  
 0.443
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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