Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Fam115eTRPM8 channel-associated factor 3; May play a role in the regulation of the cation channel TRPM8 activity. (914 aa)    
Predicted Functional Partners:
Zg16b
Prostatic spermine-binding protein; Spermine-binding protein is an androgen regulated ventral prostate glycoprotein that binds various polyamines; To mouse SBP.
      
 0.638
LOC103691965-2
Seminal vesicle secretory protein 4.
      
 0.590
Pate4
Seminal vesicle protein, secretion 7 (Predicted).
      
 0.554
Svs4
Seminal vesicle secretory protein 4.
      
 0.554
Rbp3
Retinol binding protein 3, interstitial.
      
 0.554
Wfdc3
WAP four-disulfide core domain 3 (Predicted), isoform CRA_a.
      
 0.503
LOC103691965
Seminal vesicle secretory protein 4.
      
 0.498
Aire
Autoimmune regulator.
      
 0.497
Semg1
Seminal vesicle secretory protein 2; The rat seminal vesicle contains six major androgen-dependent secretory proteins referred to as SVS I-VI. The SVS I-III proteins appear to be components of the rat copulatory plug, with the SVS II protein being the major component.
      
 0.460
Tgm4
Protein-glutamine gamma-glutamyltransferase 4; Associated with the mammalian reproductive process. Plays an important role in the formation of the seminal coagulum through the cross-linking of specific proteins present in the seminal plasma. Transglutaminase is also required to stabilize the copulatory plug.
      
 0.420
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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