| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aass | Btd | ENSRNOP00000057271 | ENSRNOP00000057779 | Alpha-aminoadipic semialdehyde synthase, mitochondrial; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine- oxoglutarate reductase and saccharopine dehydrogenase activity, respectively (By similarity). | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | 0.817 |
| Aass | Pc | ENSRNOP00000057271 | ENSRNOP00000068757 | Alpha-aminoadipic semialdehyde synthase, mitochondrial; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine- oxoglutarate reductase and saccharopine dehydrogenase activity, respectively (By similarity). | Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. | 0.409 |
| Asb14 | Btd | ENSRNOP00000017995 | ENSRNOP00000057779 | Ankyrin repeat and SOCS box protein 14; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | 0.675 |
| Asb14 | Tmem161a | ENSRNOP00000017995 | ENSRNOP00000027639 | Ankyrin repeat and SOCS box protein 14; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Transmembrane protein 161A. | 0.663 |
| Btd | Aass | ENSRNOP00000057779 | ENSRNOP00000057271 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Alpha-aminoadipic semialdehyde synthase, mitochondrial; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine- oxoglutarate reductase and saccharopine dehydrogenase activity, respectively (By similarity). | 0.817 |
| Btd | Asb14 | ENSRNOP00000057779 | ENSRNOP00000017995 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Ankyrin repeat and SOCS box protein 14; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.675 |
| Btd | C7 | ENSRNOP00000057779 | ENSRNOP00000074387 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Complement C7. | 0.555 |
| Btd | Glyctk | ENSRNOP00000057779 | ENSRNOP00000064339 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Glycerate kinase; Belongs to the glycerate kinase type-2 family. | 0.524 |
| Btd | Hlcs | ENSRNOP00000057779 | ENSRNOP00000002291 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Holocarboxylase synthetase. | 0.985 |
| Btd | Pc | ENSRNOP00000057779 | ENSRNOP00000068757 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. | 0.634 |
| Btd | Qprt | ENSRNOP00000057779 | ENSRNOP00000023080 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.570 |
| Btd | Slc5a6 | ENSRNOP00000057779 | ENSRNOP00000071291 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.618 |
| Btd | Sms | ENSRNOP00000057779 | ENSRNOP00000010135 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Spermine synthase. | 0.490 |
| Btd | Tmem161a | ENSRNOP00000057779 | ENSRNOP00000027639 | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | Transmembrane protein 161A. | 0.499 |
| C7 | Btd | ENSRNOP00000074387 | ENSRNOP00000057779 | Complement C7. | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | 0.555 |
| Glyctk | Btd | ENSRNOP00000064339 | ENSRNOP00000057779 | Glycerate kinase; Belongs to the glycerate kinase type-2 family. | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | 0.524 |
| Hlcs | Btd | ENSRNOP00000002291 | ENSRNOP00000057779 | Holocarboxylase synthetase. | Biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. | 0.985 |
| Hlcs | Pc | ENSRNOP00000002291 | ENSRNOP00000068757 | Holocarboxylase synthetase. | Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. | 0.954 |
| Hlcs | Qprt | ENSRNOP00000002291 | ENSRNOP00000023080 | Holocarboxylase synthetase. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.473 |
| Hlcs | Slc5a6 | ENSRNOP00000002291 | ENSRNOP00000071291 | Holocarboxylase synthetase. | Sodium-dependent multivitamin transporter; Transports pantothenate, biotin and lipoate in the presence of sodium; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.644 |
STRING v12.5 is now available!
