node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dab1 | Itgb1 | ENSRNOP00000009977 | ENSRNOP00000014785 | Disabled homolog 1; Adapter molecule functioning in neural development. May regulate SIAH1 activity. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.487 |
Dab1 | Lrp8 | ENSRNOP00000009977 | ENSRNOP00000017575 | Disabled homolog 1; Adapter molecule functioning in neural development. May regulate SIAH1 activity. | LDL receptor-related protein 8. | 0.992 |
Dab1 | Reln | ENSRNOP00000009977 | ENSRNOP00000058574 | Disabled homolog 1; Adapter molecule functioning in neural development. May regulate SIAH1 activity. | Reelin; Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity). | 0.968 |
Dab1 | Sh3kbp1 | ENSRNOP00000009977 | ENSRNOP00000006741 | Disabled homolog 1; Adapter molecule functioning in neural development. May regulate SIAH1 activity. | SH3 domain-containing kinase-binding protein 1; Adapter protein involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through an association with CBL and endophilins. The association with CBL, and thus the receptor internalization, may be inhibited by an interaction with PDCD6IP and/or SPRY2. Involved in regulation of ligand-dependent endocytosis of the IgE receptor. Attenuates phosphatidylinositol 3- kinase ac [...] | 0.909 |
Dab1 | Vldlr | ENSRNOP00000009977 | ENSRNOP00000036229 | Disabled homolog 1; Adapter molecule functioning in neural development. May regulate SIAH1 activity. | Very low-density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). | 0.992 |
Itga10 | Itga3 | ENSRNOP00000028812 | ENSRNOP00000034608 | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | 0.762 |
Itga10 | Itga5 | ENSRNOP00000028812 | ENSRNOP00000071805 | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | 0.780 |
Itga10 | Itga9 | ENSRNOP00000028812 | ENSRNOP00000015113 | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. | Integrin subunit alpha 9; Belongs to the integrin alpha chain family. | 0.752 |
Itga10 | Itgb1 | ENSRNOP00000028812 | ENSRNOP00000014785 | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.954 |
Itga10 | Reln | ENSRNOP00000028812 | ENSRNOP00000058574 | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. | Reelin; Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity). | 0.740 |
Itga3 | Itga10 | ENSRNOP00000034608 | ENSRNOP00000028812 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. | 0.762 |
Itga3 | Itga5 | ENSRNOP00000034608 | ENSRNOP00000071805 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | 0.954 |
Itga3 | Itga9 | ENSRNOP00000034608 | ENSRNOP00000015113 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin subunit alpha 9; Belongs to the integrin alpha chain family. | 0.914 |
Itga3 | Itgb1 | ENSRNOP00000034608 | ENSRNOP00000014785 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.997 |
Itga3 | Reln | ENSRNOP00000034608 | ENSRNOP00000058574 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Reelin; Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity). | 0.919 |
Itga5 | Itga10 | ENSRNOP00000071805 | ENSRNOP00000028812 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. | 0.780 |
Itga5 | Itga3 | ENSRNOP00000071805 | ENSRNOP00000034608 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | 0.954 |
Itga5 | Itga9 | ENSRNOP00000071805 | ENSRNOP00000015113 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin subunit alpha 9; Belongs to the integrin alpha chain family. | 0.943 |
Itga5 | Itgb1 | ENSRNOP00000071805 | ENSRNOP00000014785 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.999 |
Itga5 | Reln | ENSRNOP00000071805 | ENSRNOP00000058574 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Reelin; Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity). | 0.759 |