node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hnrnph1 | Srsf1 | ENSRNOP00000068707 | ENSRNOP00000064933 | Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity). | Serine and arginine-rich-splicing factor 1. | 0.815 |
Hnrnph1 | Srsf2 | ENSRNOP00000068707 | ENSRNOP00000059012 | Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity). | Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment (By similarity). | 0.910 |
Hnrnph1 | Srsf3 | ENSRNOP00000068707 | ENSRNOP00000000627 | Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity). | Serine and arginine-rich-splicing factor 3. | 0.807 |
Hnrnph1 | Srsf5 | ENSRNOP00000068707 | ENSRNOP00000007583 | Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity). | Serine/arginine-rich splicing factor 5; May be required for progression through G1 and entry into S phase of cell growth. May play a regulatory role in pre-mRNA splicing. Autoregulates its own expression. Plays a role in constitutive splicing and can modulate the selection of alternative splice sites (By similarity). Could play an important role in development and differentiation in the spleen and thymus. | 0.718 |
Hnrnph1 | Srsf7 | ENSRNOP00000068707 | ENSRNOP00000035155 | Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity). | Serine and arginine-rich-splicing factor 7. | 0.810 |
Hnrnph1 | Srsf9 | ENSRNOP00000068707 | ENSRNOP00000001539 | Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity). | Serine/arginine-rich splicing factor 9; Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10 (By similarity); Belongs to the splicing factor SR family. | 0.677 |
Hnrnph1 | U2af1 | ENSRNOP00000068707 | ENSRNOP00000067005 | Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity). | U2 small nuclear RNA auxiliary factor 1. | 0.408 |
Hnrnph1 | U2af2 | ENSRNOP00000068707 | ENSRNOP00000021392 | Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity). | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.619 |
Srpk1 | Srsf1 | ENSRNOP00000075811 | ENSRNOP00000064933 | SRSF protein kinase 1. | Serine and arginine-rich-splicing factor 1. | 0.992 |
Srpk1 | Srsf2 | ENSRNOP00000075811 | ENSRNOP00000059012 | SRSF protein kinase 1. | Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment (By similarity). | 0.967 |
Srpk1 | Srsf3 | ENSRNOP00000075811 | ENSRNOP00000000627 | SRSF protein kinase 1. | Serine and arginine-rich-splicing factor 3. | 0.955 |
Srpk1 | Srsf5 | ENSRNOP00000075811 | ENSRNOP00000007583 | SRSF protein kinase 1. | Serine/arginine-rich splicing factor 5; May be required for progression through G1 and entry into S phase of cell growth. May play a regulatory role in pre-mRNA splicing. Autoregulates its own expression. Plays a role in constitutive splicing and can modulate the selection of alternative splice sites (By similarity). Could play an important role in development and differentiation in the spleen and thymus. | 0.972 |
Srpk1 | Srsf7 | ENSRNOP00000075811 | ENSRNOP00000035155 | SRSF protein kinase 1. | Serine and arginine-rich-splicing factor 7. | 0.947 |
Srpk1 | Srsf9 | ENSRNOP00000075811 | ENSRNOP00000001539 | SRSF protein kinase 1. | Serine/arginine-rich splicing factor 9; Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10 (By similarity); Belongs to the splicing factor SR family. | 0.965 |
Srpk1 | U2af1 | ENSRNOP00000075811 | ENSRNOP00000067005 | SRSF protein kinase 1. | U2 small nuclear RNA auxiliary factor 1. | 0.478 |
Srpk1 | U2af2 | ENSRNOP00000075811 | ENSRNOP00000021392 | SRSF protein kinase 1. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.743 |
Srsf1 | Hnrnph1 | ENSRNOP00000064933 | ENSRNOP00000068707 | Serine and arginine-rich-splicing factor 1. | Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) (By similarity). | 0.815 |
Srsf1 | Srpk1 | ENSRNOP00000064933 | ENSRNOP00000075811 | Serine and arginine-rich-splicing factor 1. | SRSF protein kinase 1. | 0.992 |
Srsf1 | Srsf2 | ENSRNOP00000064933 | ENSRNOP00000059012 | Serine and arginine-rich-splicing factor 1. | Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment (By similarity). | 0.979 |
Srsf1 | Srsf3 | ENSRNOP00000064933 | ENSRNOP00000000627 | Serine and arginine-rich-splicing factor 1. | Serine and arginine-rich-splicing factor 3. | 0.978 |