node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cd151 | Cd19 | ENSRNOP00000066223 | ENSRNOP00000051906 | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | CD19 molecule. | 0.514 |
Cd151 | Cd37 | ENSRNOP00000066223 | ENSRNOP00000059092 | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | Leukocyte antigen CD37. | 0.576 |
Cd151 | Cd53 | ENSRNOP00000066223 | ENSRNOP00000024344 | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); Belongs to the tetraspanin (TM4SF) family. | 0.572 |
Cd151 | Cd63 | ENSRNOP00000066223 | ENSRNOP00000071571 | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | CD63 antigen; Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal tr [...] | 0.859 |
Cd151 | Cd81 | ENSRNOP00000066223 | ENSRNOP00000027760 | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | 0.828 |
Cd151 | Cd82 | ENSRNOP00000066223 | ENSRNOP00000000052 | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | CD82 antigen; Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway. | 0.681 |
Cd151 | Tsg101 | ENSRNOP00000066223 | ENSRNOP00000018194 | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). It may also play a role in the [...] | 0.442 |
Cd151-2 | Cd19 | ENSRNOP00000073673 | ENSRNOP00000051906 | CD151 antigen-like. | CD19 molecule. | 0.514 |
Cd151-2 | Cd37 | ENSRNOP00000073673 | ENSRNOP00000059092 | CD151 antigen-like. | Leukocyte antigen CD37. | 0.576 |
Cd151-2 | Cd53 | ENSRNOP00000073673 | ENSRNOP00000024344 | CD151 antigen-like. | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); Belongs to the tetraspanin (TM4SF) family. | 0.572 |
Cd151-2 | Cd63 | ENSRNOP00000073673 | ENSRNOP00000071571 | CD151 antigen-like. | CD63 antigen; Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal tr [...] | 0.863 |
Cd151-2 | Cd81 | ENSRNOP00000073673 | ENSRNOP00000027760 | CD151 antigen-like. | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | 0.822 |
Cd151-2 | Cd82 | ENSRNOP00000073673 | ENSRNOP00000000052 | CD151 antigen-like. | CD82 antigen; Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway. | 0.681 |
Cd151-2 | Tsg101 | ENSRNOP00000073673 | ENSRNOP00000018194 | CD151 antigen-like. | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). It may also play a role in the [...] | 0.443 |
Cd19 | Cd151 | ENSRNOP00000051906 | ENSRNOP00000066223 | CD19 molecule. | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. | 0.514 |
Cd19 | Cd151-2 | ENSRNOP00000051906 | ENSRNOP00000073673 | CD19 molecule. | CD151 antigen-like. | 0.514 |
Cd19 | Cd37 | ENSRNOP00000051906 | ENSRNOP00000059092 | CD19 molecule. | Leukocyte antigen CD37. | 0.792 |
Cd19 | Cd53 | ENSRNOP00000051906 | ENSRNOP00000024344 | CD19 molecule. | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); Belongs to the tetraspanin (TM4SF) family. | 0.472 |
Cd19 | Cd63 | ENSRNOP00000051906 | ENSRNOP00000071571 | CD19 molecule. | CD63 antigen; Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal tr [...] | 0.608 |
Cd19 | Cd81 | ENSRNOP00000051906 | ENSRNOP00000027760 | CD19 molecule. | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | 0.999 |