STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmem243Similar to chromosome 7 open reading frame 23 (Predicted), isoform CRA_b. (118 aa)    
Predicted Functional Partners:
Pigz
Mannosyltransferase.
      
 0.730
Pigz-2
Phosphatidylinositol glycan anchor biosynthesis, class Z.
      
 0.730
Rundc3b
RUN domain-containing protein 3B.
      
 0.659
Slc25a40
Solute carrier family 25 member 40.
      
 0.637
Tti2
TELO2-interacting protein 2; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs (By similarity); Belongs to the TTI2 family.
      
 0.633
Tmem14a-2
Transmembrane protein 14A (Predicted), isoform CRA_b.
      
 0.628
Tmem14a
Transmembrane protein 14A.
      
 0.628
Dmtf1
Cyclin-D-binding Myb-like transcription factor 1; Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53- dependent growth arrest. Binds to the consensus sequence 5'- CCCG[GT]ATGT-3'.
      
 0.609
Zfp653
RCG31652, isoform CRA_b.
      
 0.582
Riok1
Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
      
 0.571
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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