node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fah | Fahd1 | ENSRNOP00000061132 | ENSRNOP00000019767 | Fumarylacetoacetase; Belongs to the FAH family. | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | 0.964 |
Fah | Fh | ENSRNOP00000061132 | ENSRNOP00000004917 | Fumarylacetoacetase; Belongs to the FAH family. | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (By similarity). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [Isoform Cytoplasmic]: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity). Also plays a role in DNA repair by promoting [...] | 0.880 |
Fah | Gstz1 | ENSRNOP00000061132 | ENSRNOP00000065390 | Fumarylacetoacetase; Belongs to the FAH family. | Maleylacetoacetate isomerase; Probable bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2- oxa-1, 3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with t-butyl and cumene hydroperoxides (By similarity). Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. | 0.995 |
Fah | Hgd | ENSRNOP00000061132 | ENSRNOP00000003645 | Fumarylacetoacetase; Belongs to the FAH family. | Homogentisate 1, 2-dioxygenase. | 0.958 |
Fah | Hpd | ENSRNOP00000061132 | ENSRNOP00000001809 | Fumarylacetoacetase; Belongs to the FAH family. | 4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine. | 0.912 |
Fah | Rag2 | ENSRNOP00000061132 | ENSRNOP00000006097 | Fumarylacetoacetase; Belongs to the FAH family. | Recombination-activating 2. | 0.800 |
Fah | Sdha | ENSRNOP00000061132 | ENSRNOP00000018336 | Fumarylacetoacetase; Belongs to the FAH family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.857 |
Fah | Sdhb | ENSRNOP00000061132 | ENSRNOP00000010593 | Fumarylacetoacetase; Belongs to the FAH family. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.824 |
Fah | Sdhc | ENSRNOP00000061132 | ENSRNOP00000004228 | Fumarylacetoacetase; Belongs to the FAH family. | Succinate dehydrogenase complex, subunit C, integral membrane protein, isoform CRA_b. | 0.815 |
Fah | Sdhd | ENSRNOP00000061132 | ENSRNOP00000055942 | Fumarylacetoacetase; Belongs to the FAH family. | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. | 0.806 |
Fahd1 | Fah | ENSRNOP00000019767 | ENSRNOP00000061132 | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | Fumarylacetoacetase; Belongs to the FAH family. | 0.964 |
Fahd1 | Fh | ENSRNOP00000019767 | ENSRNOP00000004917 | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (By similarity). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [Isoform Cytoplasmic]: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity). Also plays a role in DNA repair by promoting [...] | 0.859 |
Fahd1 | Gstz1 | ENSRNOP00000019767 | ENSRNOP00000065390 | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | Maleylacetoacetate isomerase; Probable bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2- oxa-1, 3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with t-butyl and cumene hydroperoxides (By similarity). Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. | 0.478 |
Fahd1 | Hgd | ENSRNOP00000019767 | ENSRNOP00000003645 | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | Homogentisate 1, 2-dioxygenase. | 0.819 |
Fahd1 | Hpd | ENSRNOP00000019767 | ENSRNOP00000001809 | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | 4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine. | 0.445 |
Fahd1 | Sdha | ENSRNOP00000019767 | ENSRNOP00000018336 | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.857 |
Fahd1 | Sdhb | ENSRNOP00000019767 | ENSRNOP00000010593 | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.827 |
Fahd1 | Sdhc | ENSRNOP00000019767 | ENSRNOP00000004228 | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | Succinate dehydrogenase complex, subunit C, integral membrane protein, isoform CRA_b. | 0.815 |
Fahd1 | Sdhd | ENSRNOP00000019767 | ENSRNOP00000055942 | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. | 0.809 |
Fh | Fah | ENSRNOP00000004917 | ENSRNOP00000061132 | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (By similarity). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [Isoform Cytoplasmic]: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity). Also plays a role in DNA repair by promoting [...] | Fumarylacetoacetase; Belongs to the FAH family. | 0.880 |