| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C1s | Ccdc6 | ENSRNOP00000016330 | ENSRNOP00000033185 | Complement C1s subcomponent heavy chain; C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4 (By similarity). | Coiled-coil domain-containing 6. | 0.784 |
| C1s | Ppp4r1 | ENSRNOP00000016330 | ENSRNOP00000061977 | Complement C1s subcomponent heavy chain; C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4 (By similarity). | Serine/threonine-protein phosphatase 4 regulatory subunit 1; Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3 (By similarity). | 0.824 |
| Ccdc6 | C1s | ENSRNOP00000033185 | ENSRNOP00000016330 | Coiled-coil domain-containing 6. | Complement C1s subcomponent heavy chain; C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4 (By similarity). | 0.784 |
| Ccdc6 | LOC100362453 | ENSRNOP00000033185 | ENSRNOP00000070579 | Coiled-coil domain-containing 6. | Serine/threonine-protein phosphatase. | 0.503 |
| Ccdc6 | LOC103694903 | ENSRNOP00000033185 | ENSRNOP00000071286 | Coiled-coil domain-containing 6. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform. | 0.503 |
| Ccdc6 | Ppp2ca | ENSRNOP00000033185 | ENSRNOP00000007621 | Coiled-coil domain-containing 6. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). Belongs to the PPP phosphatase family. PP-1 subfamily. | 0.503 |
| Ccdc6 | Ppp2cb | ENSRNOP00000033185 | ENSRNOP00000020663 | Coiled-coil domain-containing 6. | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. | 0.503 |
| Ccdc6 | Ppp4c | ENSRNOP00000033185 | ENSRNOP00000026909 | Coiled-coil domain-containing 6. | Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...] | 0.909 |
| Ccdc6 | Ppp4r1 | ENSRNOP00000033185 | ENSRNOP00000061977 | Coiled-coil domain-containing 6. | Serine/threonine-protein phosphatase 4 regulatory subunit 1; Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3 (By similarity). | 0.926 |
| Ccdc6 | Ppp4r2 | ENSRNOP00000033185 | ENSRNOP00000030661 | Coiled-coil domain-containing 6. | Protein phosphatase 4, regulatory subunit 2. | 0.802 |
| LOC100362453 | Ccdc6 | ENSRNOP00000070579 | ENSRNOP00000033185 | Serine/threonine-protein phosphatase. | Coiled-coil domain-containing 6. | 0.503 |
| LOC100362453 | Ppp2r2b | ENSRNOP00000070579 | ENSRNOP00000071716 | Serine/threonine-protein phosphatase. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance. | 0.882 |
| LOC100362453 | Ppp4c | ENSRNOP00000070579 | ENSRNOP00000026909 | Serine/threonine-protein phosphatase. | Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...] | 0.663 |
| LOC100362453 | Ppp4r1 | ENSRNOP00000070579 | ENSRNOP00000061977 | Serine/threonine-protein phosphatase. | Serine/threonine-protein phosphatase 4 regulatory subunit 1; Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3 (By similarity). | 0.703 |
| LOC100362453 | Ppp4r2 | ENSRNOP00000070579 | ENSRNOP00000030661 | Serine/threonine-protein phosphatase. | Protein phosphatase 4, regulatory subunit 2. | 0.413 |
| LOC103694903 | Ccdc6 | ENSRNOP00000071286 | ENSRNOP00000033185 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform. | Coiled-coil domain-containing 6. | 0.503 |
| LOC103694903 | Ppp2cb | ENSRNOP00000071286 | ENSRNOP00000020663 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform. | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. | 0.830 |
| LOC103694903 | Ppp2r2b | ENSRNOP00000071286 | ENSRNOP00000071716 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance. | 0.960 |
| LOC103694903 | Ppp4c | ENSRNOP00000071286 | ENSRNOP00000026909 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform. | Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...] | 0.663 |
| LOC103694903 | Ppp4r1 | ENSRNOP00000071286 | ENSRNOP00000061977 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform. | Serine/threonine-protein phosphatase 4 regulatory subunit 1; Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3 (By similarity). | 0.655 |
