node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cav1 | Dnm2 | ENSRNOP00000073712 | ENSRNOP00000010948 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Dynamin-2; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse- containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity). Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.982 |
Cav1 | Nos3 | ENSRNOP00000073712 | ENSRNOP00000013058 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. | 0.975 |
Cav1 | Nostrin | ENSRNOP00000073712 | ENSRNOP00000062066 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Nostrin; Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. | 0.534 |
Churc1 | Fn3krp | ENSRNOP00000009620 | ENSRNOP00000051799 | Churchill domain-containing 1. | Fructosamine-3-kinase-related protein; Belongs to the fructosamine kinase family. | 0.535 |
Churc1 | Marchf6 | ENSRNOP00000009620 | ENSRNOP00000028561 | Churchill domain-containing 1. | Membrane associated ring-CH-type finger 6. | 0.510 |
Churc1 | Nostrin | ENSRNOP00000009620 | ENSRNOP00000062066 | Churchill domain-containing 1. | Nostrin; Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. | 0.573 |
Churc1 | Ufsp1 | ENSRNOP00000009620 | ENSRNOP00000067476 | Churchill domain-containing 1. | UFM1-specific peptidase 1. | 0.488 |
Dnm2 | Cav1 | ENSRNOP00000010948 | ENSRNOP00000073712 | Dynamin-2; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse- containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity). Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | 0.982 |
Dnm2 | Nos3 | ENSRNOP00000010948 | ENSRNOP00000013058 | Dynamin-2; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse- containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity). Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. | 0.644 |
Dnm2 | Nostrin | ENSRNOP00000010948 | ENSRNOP00000062066 | Dynamin-2; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse- containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity). Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Nostrin; Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. | 0.500 |
Fn3krp | Churc1 | ENSRNOP00000051799 | ENSRNOP00000009620 | Fructosamine-3-kinase-related protein; Belongs to the fructosamine kinase family. | Churchill domain-containing 1. | 0.535 |
Fn3krp | Inpp5e | ENSRNOP00000051799 | ENSRNOP00000073935 | Fructosamine-3-kinase-related protein; Belongs to the fructosamine kinase family. | Phosphatidylinositol polyphosphate 5-phosphatase type IV; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate PtdIns (4,5)P2 and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Specific for lipid substrates, inactive towards water soluble inositol phosphates (By similarity). Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3- kinase (PI3K) signaling and stability (By similarity). Belongs to the ino [...] | 0.422 |
Fn3krp | Marchf6 | ENSRNOP00000051799 | ENSRNOP00000028561 | Fructosamine-3-kinase-related protein; Belongs to the fructosamine kinase family. | Membrane associated ring-CH-type finger 6. | 0.524 |
Fn3krp | Nostrin | ENSRNOP00000051799 | ENSRNOP00000062066 | Fructosamine-3-kinase-related protein; Belongs to the fructosamine kinase family. | Nostrin; Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. | 0.620 |
Fn3krp | Ufsp1 | ENSRNOP00000051799 | ENSRNOP00000067476 | Fructosamine-3-kinase-related protein; Belongs to the fructosamine kinase family. | UFM1-specific peptidase 1. | 0.495 |
Inpp5e | Fn3krp | ENSRNOP00000073935 | ENSRNOP00000051799 | Phosphatidylinositol polyphosphate 5-phosphatase type IV; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate PtdIns (4,5)P2 and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Specific for lipid substrates, inactive towards water soluble inositol phosphates (By similarity). Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3- kinase (PI3K) signaling and stability (By similarity). Belongs to the ino [...] | Fructosamine-3-kinase-related protein; Belongs to the fructosamine kinase family. | 0.422 |
Inpp5e | Nostrin | ENSRNOP00000073935 | ENSRNOP00000062066 | Phosphatidylinositol polyphosphate 5-phosphatase type IV; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate PtdIns (4,5)P2 and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Specific for lipid substrates, inactive towards water soluble inositol phosphates (By similarity). Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3- kinase (PI3K) signaling and stability (By similarity). Belongs to the ino [...] | Nostrin; Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. | 0.478 |
Marchf6 | Churc1 | ENSRNOP00000028561 | ENSRNOP00000009620 | Membrane associated ring-CH-type finger 6. | Churchill domain-containing 1. | 0.510 |
Marchf6 | Fn3krp | ENSRNOP00000028561 | ENSRNOP00000051799 | Membrane associated ring-CH-type finger 6. | Fructosamine-3-kinase-related protein; Belongs to the fructosamine kinase family. | 0.524 |
Marchf6 | Nostrin | ENSRNOP00000028561 | ENSRNOP00000062066 | Membrane associated ring-CH-type finger 6. | Nostrin; Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. | 0.579 |