node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atox1 | Mt1 | ENSRNOP00000017588 | ENSRNOP00000054706 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | 0.627 |
Atox1 | Mt1m | ENSRNOP00000017588 | ENSRNOP00000041060 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.721 |
Atox1 | Mt2A | ENSRNOP00000017588 | ENSRNOP00000062585 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | 0.450 |
Atox1 | Mt3 | ENSRNOP00000017588 | ENSRNOP00000025669 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family. | 0.498 |
Atox1 | Slc30a1 | ENSRNOP00000017588 | ENSRNOP00000006340 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Zinc transporter 1; May be involved in zinc transport out of the cell. | 0.586 |
Cebpa | Mt2A | ENSRNOP00000063123 | ENSRNOP00000062585 | CCAAT/enhancer-binding protein alpha; Transcription factor that coordinates proliferation arrest and the differentiation of myeloid progenitors, adipocytes, hepatocytes, and cells of the lung and the placenta. Binds directly to the consensus DNA sequence 5'-T[TG]NNGNAA[TG]-3' acting as an activator on distinct target genes. During early embryogenesis, plays essential and redundant functions with CEBPB (By similarity). Essential for the transition from common myeloid progenitors (CMP) to granulocyte/monocyte progenitors (GMP). Critical for the proper development of the liver and the lun [...] | Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | 0.516 |
Mc3r | Mt1m | ENSRNOP00000005871 | ENSRNOP00000041060 | Melanocortin receptor 3; Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.512 |
Mc3r | Mt2A | ENSRNOP00000005871 | ENSRNOP00000062585 | Melanocortin receptor 3; Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. | Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | 0.459 |
Mc4r | Mt1m | ENSRNOP00000025223 | ENSRNOP00000041060 | Melanocortin receptor 4; Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). Belongs to the G-protein coupled receptor 1 family. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.556 |
Mc4r | Mt2A | ENSRNOP00000025223 | ENSRNOP00000062585 | Melanocortin receptor 4; Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). Belongs to the G-protein coupled receptor 1 family. | Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | 0.592 |
Mt1 | Atox1 | ENSRNOP00000054706 | ENSRNOP00000017588 | Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | 0.627 |
Mt1 | Mt1m | ENSRNOP00000054706 | ENSRNOP00000041060 | Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | 0.997 |
Mt1 | Mt2A | ENSRNOP00000054706 | ENSRNOP00000062585 | Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | 0.977 |
Mt1 | Mt3 | ENSRNOP00000054706 | ENSRNOP00000025669 | Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family. | 0.546 |
Mt1 | Slc30a1 | ENSRNOP00000054706 | ENSRNOP00000006340 | Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | Zinc transporter 1; May be involved in zinc transport out of the cell. | 0.737 |
Mt1 | Slc30a2 | ENSRNOP00000054706 | ENSRNOP00000072908 | Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | Zinc transporter 2; Involved in accumulation of zinc in endosomal/lysosomal vesicles. | 0.544 |
Mt1m | Atox1 | ENSRNOP00000041060 | ENSRNOP00000017588 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | 0.721 |
Mt1m | Mc3r | ENSRNOP00000041060 | ENSRNOP00000005871 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | Melanocortin receptor 3; Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. | 0.512 |
Mt1m | Mc4r | ENSRNOP00000041060 | ENSRNOP00000025223 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | Melanocortin receptor 4; Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). Belongs to the G-protein coupled receptor 1 family. | 0.556 |
Mt1m | Mt1 | ENSRNOP00000041060 | ENSRNOP00000054706 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. | Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. | 0.997 |