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Ece1 protein (Rattus norvegicus) - STRING interaction network
"Ece1" - Endothelin-converting enzyme 1 in Rattus norvegicus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
Ece1Endothelin-converting enzyme 1; Converts big endothelin-1 to endothelin-1; Belongs to the peptidase M13 family (753 aa)    
Predicted Functional Partners:
Edn1
Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (202 aa)
     
  0.991
Edn3
Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides (167 aa)
       
 
  0.786
Ednra
Endothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is- ET1 > ET2 >> ET3; Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily (426 aa)
           
  0.747
Ednrb
Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (442 aa)
           
  0.727
Ide
Insulin-degrading enzyme; Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP; Belongs to the peptidase M16 family (1019 aa)
           
  0.708
Tsr1
TSR1, ribosome maturation factor; TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) (804 aa)
           
  0.680
Lias
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (373 aa)
           
  0.676
Edn2
Endothelin-2; Vasoconstrictor (176 aa)
       
 
  0.675
Spint1
Serine peptidase inhibitor, Kunitz type 1 (507 aa)
           
  0.673
Naglu
N-acetyl-alpha-glucosaminidase; N-acetylglucosaminidase, alpha (739 aa)
     
   
  0.626
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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