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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103690002Histone H2A.J. (129 aa)    
Predicted Functional Partners:
H2bc12
Histone H2B; Belongs to the histone H2B family.
 
 
 0.749
A0A0G2K7R1_RAT
Histone domain-containing protein; Belongs to the histone H2B family.
  
 
 0.670
Hist1h2bd
Histone H2B; Belongs to the histone H2B family.
 
 
 0.628
Hist1h2bc
Histone H2B type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.627
H2bc1
Histone H2B type 1-A; Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells. Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large- scale exchange of histones. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcrip [...]
 
 
 0.586
Hist2h2be
Histone H2B; Belongs to the histone H2B family.
 
 
 0.586
Hist3h2ba
Histone H2B; Belongs to the histone H2B family.
 
 
 0.581
LOC102549061
Histone H2B; Belongs to the histone H2B family.
 
 
 0.581
H2bc9
Histone H2B; Belongs to the histone H2B family.
 
 
 0.581
Hist1h2bc-2
Similar to Histone H2B 291B.
 
 
 0.580
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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