Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ccdc106 | Fbxo9 | ENSRNOP00000021613 | ENSRNOP00000010961 | Coiled-coil domain-containing 106. | F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTOR [...] | 0.695 |
| Ccdc106 | Fiz1 | ENSRNOP00000021613 | ENSRNOP00000022236 | Coiled-coil domain-containing 106. | Similar to Flt3 interacting zinc finger protein 1 (Predicted). | 0.696 |
| Ccdc106 | Mrps34 | ENSRNOP00000021613 | ENSRNOP00000021075 | Coiled-coil domain-containing 106. | Mitochondrial ribosomal protein S34 (Predicted), isoform CRA_a. | 0.700 |
| Ccdc106 | Nudt13 | ENSRNOP00000021613 | ENSRNOP00000064470 | Coiled-coil domain-containing 106. | Nudix hydrolase 13. | 0.771 |
| Ccdc106 | Rcbtb1 | ENSRNOP00000021613 | ENSRNOP00000038352 | Coiled-coil domain-containing 106. | RCC1 and BTB domain-containing protein 1. | 0.750 |
| Ccdc106 | Rspry1 | ENSRNOP00000021613 | ENSRNOP00000071830 | Coiled-coil domain-containing 106. | Ring finger and SPRY domain-containing 1. | 0.829 |
| Ccdc106 | Zc3h15 | ENSRNOP00000021613 | ENSRNOP00000007276 | Coiled-coil domain-containing 106. | Zinc finger CCCH domain-containing protein 15; Protects DRG1 from proteolytic degradation. Stimulates DRG1 GTPase activity likely by increasing the affinity for the potassium ions. | 0.747 |
| Ephx2 | Nudt13 | ENSRNOP00000023385 | ENSRNOP00000064470 | Bifunctional epoxide hydrolase 2; Bifunctional enzyme. The C- terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators (By similarity). The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy- hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy- hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphon [...] | Nudix hydrolase 13. | 0.957 |
| Ephx2 | Nudt15 | ENSRNOP00000023385 | ENSRNOP00000072456 | Bifunctional epoxide hydrolase 2; Bifunctional enzyme. The C- terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators (By similarity). The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy- hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy- hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphon [...] | Nudix (Nucleoside diphosphate linked moiety X)-type motif 15 (Predicted); Belongs to the Nudix hydrolase family. | 0.558 |
| Fbxo9 | Ccdc106 | ENSRNOP00000010961 | ENSRNOP00000021613 | F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTOR [...] | Coiled-coil domain-containing 106. | 0.695 |
| Fbxo9 | Fiz1 | ENSRNOP00000010961 | ENSRNOP00000022236 | F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTOR [...] | Similar to Flt3 interacting zinc finger protein 1 (Predicted). | 0.551 |
| Fbxo9 | Mrps34 | ENSRNOP00000010961 | ENSRNOP00000021075 | F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTOR [...] | Mitochondrial ribosomal protein S34 (Predicted), isoform CRA_a. | 0.597 |
| Fbxo9 | Nudt13 | ENSRNOP00000010961 | ENSRNOP00000064470 | F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTOR [...] | Nudix hydrolase 13. | 0.650 |
| Fbxo9 | Rcbtb1 | ENSRNOP00000010961 | ENSRNOP00000038352 | F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTOR [...] | RCC1 and BTB domain-containing protein 1. | 0.600 |
| Fbxo9 | Rspry1 | ENSRNOP00000010961 | ENSRNOP00000071830 | F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTOR [...] | Ring finger and SPRY domain-containing 1. | 0.662 |
| Fbxo9 | Zc3h15 | ENSRNOP00000010961 | ENSRNOP00000007276 | F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTOR [...] | Zinc finger CCCH domain-containing protein 15; Protects DRG1 from proteolytic degradation. Stimulates DRG1 GTPase activity likely by increasing the affinity for the potassium ions. | 0.613 |
| Fiz1 | Ccdc106 | ENSRNOP00000022236 | ENSRNOP00000021613 | Similar to Flt3 interacting zinc finger protein 1 (Predicted). | Coiled-coil domain-containing 106. | 0.696 |
| Fiz1 | Fbxo9 | ENSRNOP00000022236 | ENSRNOP00000010961 | Similar to Flt3 interacting zinc finger protein 1 (Predicted). | F-box only protein 9; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTOR [...] | 0.551 |
| Fiz1 | Mrps34 | ENSRNOP00000022236 | ENSRNOP00000021075 | Similar to Flt3 interacting zinc finger protein 1 (Predicted). | Mitochondrial ribosomal protein S34 (Predicted), isoform CRA_a. | 0.645 |
| Fiz1 | Nudt13 | ENSRNOP00000022236 | ENSRNOP00000064470 | Similar to Flt3 interacting zinc finger protein 1 (Predicted). | Nudix hydrolase 13. | 0.655 |
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