STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GaaLysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (953 aa)    
Predicted Functional Partners:
Amy2a3
Pancreatic alpha-amylase-like
  
 
 0.979
Gla
Alpha-galactosidase; Galactosidase, alpha
  
 
 0.977
Amy1a
Alpha-amylase; Amylase, alpha 1A (salivary)
  
 
 0.969
LOC103689940
Pancreatic alpha-amylase-like; Alpha-amylase; Amylase 2a3
  
 
 0.969
Hk3
Hexokinase-3; Hexokinase 3 (white cell); Belongs to the hexokinase family
   
 
 0.968
Hk2
Hexokinase-2; Hexokinase 2; Belongs to the hexokinase family
   
 
 0.925
ENSRNOP00000064051
Hexokinase 1-like; Belongs to the hexokinase family
   
 
 0.925
Gyg1
Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase
   
 
 0.921
Gba3
Glucosidase, beta, acid 3 (cytosolic) (predicted); Glucosidase, beta, acid 3; Belongs to the glycosyl hydrolase 1 family
  
 
 0.914
Ganc
Glucosidase, alpha; neutral C; Belongs to the glycosyl hydrolase 31 family
  
 
0.855
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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