STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Muc2Mucin-2; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer (By similarity). (2391 aa)    
Predicted Functional Partners:
Muc13
Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
   
 0.824
Muc1
Mucin 1, cell surface-associated.
    
 0.786
Muc16
Uncharacterized protein.
    
 0.782
Muc4
Mucin-4.
   
 
 0.768
Muc20
Mucin 20 (Predicted), isoform CRA_a.
    
 0.681
Muc15
Mucin 15, cell surface-associated.
    
 0.647
Muc6
Mucin 6, oligomeric mucus/gel-forming.
    
0.624
Cdx2
Caudal type homeo box 2.
   
  
 0.601
Ocln
Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. May be involved in the organization of actin in endothelial cells. Belongs to the ELL/occludin family.
    
 
 0.578
Muc5b
Mucin 5B, oligomeric mucus/gel-forming.
     
0.557
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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