node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccnt1 | Ccnt2 | ENSRNOP00000073281 | ENSRNOP00000024602 | Cyclin T1 (Predicted); Belongs to the cyclin family. | Cyclin T2 (Predicted); Belongs to the cyclin family. | 0.927 |
Ccnt1 | Cdk9 | ENSRNOP00000073281 | ENSRNOP00000037778 | Cyclin T1 (Predicted); Belongs to the cyclin family. | Cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR and the negative elongation factors DSIF and NELF. Regulates cytoki [...] | 0.999 |
Ccnt1 | Hexim1 | ENSRNOP00000073281 | ENSRNOP00000004272 | Cyclin T1 (Predicted); Belongs to the cyclin family. | Protein HEXIM1; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA- dependent transcriptional activity. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP- RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response [...] | 0.867 |
Ccnt1 | Hexim2 | ENSRNOP00000073281 | ENSRNOP00000052039 | Cyclin T1 (Predicted); Belongs to the cyclin family. | Hexamthylene bis-acetamide inducible 2 (Predicted). | 0.723 |
Ccnt1 | LOC100910540 | ENSRNOP00000073281 | ENSRNOP00000001871 | Cyclin T1 (Predicted); Belongs to the cyclin family. | 7SK snRNA methylphosphate-capping enzyme-like. | 0.713 |
Ccnt1 | LOC103692976 | ENSRNOP00000073281 | ENSRNOP00000070328 | Cyclin T1 (Predicted); Belongs to the cyclin family. | Cyclin-T1-like. | 0.921 |
Ccnt1 | Larp7 | ENSRNOP00000073281 | ENSRNOP00000065357 | Cyclin T1 (Predicted); Belongs to the cyclin family. | La-related protein 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. | 0.732 |
Ccnt1 | Mepce | ENSRNOP00000073281 | ENSRNOP00000067286 | Cyclin T1 (Predicted); Belongs to the cyclin family. | Methylphosphate capping enzyme. | 0.702 |
Ccnt2 | Ccnt1 | ENSRNOP00000024602 | ENSRNOP00000073281 | Cyclin T2 (Predicted); Belongs to the cyclin family. | Cyclin T1 (Predicted); Belongs to the cyclin family. | 0.927 |
Ccnt2 | Cdk9 | ENSRNOP00000024602 | ENSRNOP00000037778 | Cyclin T2 (Predicted); Belongs to the cyclin family. | Cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR and the negative elongation factors DSIF and NELF. Regulates cytoki [...] | 0.999 |
Ccnt2 | Hexim1 | ENSRNOP00000024602 | ENSRNOP00000004272 | Cyclin T2 (Predicted); Belongs to the cyclin family. | Protein HEXIM1; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA- dependent transcriptional activity. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP- RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response [...] | 0.895 |
Ccnt2 | Hexim2 | ENSRNOP00000024602 | ENSRNOP00000052039 | Cyclin T2 (Predicted); Belongs to the cyclin family. | Hexamthylene bis-acetamide inducible 2 (Predicted). | 0.735 |
Ccnt2 | LOC100910540 | ENSRNOP00000024602 | ENSRNOP00000001871 | Cyclin T2 (Predicted); Belongs to the cyclin family. | 7SK snRNA methylphosphate-capping enzyme-like. | 0.606 |
Ccnt2 | LOC103692976 | ENSRNOP00000024602 | ENSRNOP00000070328 | Cyclin T2 (Predicted); Belongs to the cyclin family. | Cyclin-T1-like. | 0.937 |
Ccnt2 | Larp7 | ENSRNOP00000024602 | ENSRNOP00000065357 | Cyclin T2 (Predicted); Belongs to the cyclin family. | La-related protein 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. | 0.822 |
Ccnt2 | Mepce | ENSRNOP00000024602 | ENSRNOP00000067286 | Cyclin T2 (Predicted); Belongs to the cyclin family. | Methylphosphate capping enzyme. | 0.629 |
Cdk9 | Ccnt1 | ENSRNOP00000037778 | ENSRNOP00000073281 | Cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR and the negative elongation factors DSIF and NELF. Regulates cytoki [...] | Cyclin T1 (Predicted); Belongs to the cyclin family. | 0.999 |
Cdk9 | Ccnt2 | ENSRNOP00000037778 | ENSRNOP00000024602 | Cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR and the negative elongation factors DSIF and NELF. Regulates cytoki [...] | Cyclin T2 (Predicted); Belongs to the cyclin family. | 0.999 |
Cdk9 | Hexim1 | ENSRNOP00000037778 | ENSRNOP00000004272 | Cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR and the negative elongation factors DSIF and NELF. Regulates cytoki [...] | Protein HEXIM1; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA- dependent transcriptional activity. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP- RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response [...] | 0.979 |
Cdk9 | Hexim2 | ENSRNOP00000037778 | ENSRNOP00000052039 | Cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR and the negative elongation factors DSIF and NELF. Regulates cytoki [...] | Hexamthylene bis-acetamide inducible 2 (Predicted). | 0.926 |