Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Il17rbInterleukin 17 receptor B (Predicted), isoform CRA_b. (354 aa)    
Predicted Functional Partners:
Il25
Interleukin 25.
    
 0.995
Il17b
Interleukin 17B, isoform CRA_a.
    
 0.968
Il17ra
Interleukin 17 receptor A.
   
0.948
Traf3ip2
Chromosome 6 open reading frame 4, isoform CRA_a.
    
 0.933
Traf6
TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]
    
 0.926
Tradd
TNFRSF1A-associated via death domain.
     
  0.884
Chdh
Choline dehydrogenase, mitochondrial; Belongs to the GMC oxidoreductase family.
   
 
 0.832
Il17re
Interleukin-17 receptor E; Specific functional receptor for IL17C, signaling through the NF-kappa-B and MAPK pathways. Requires TRAF3IP2 /ACT1 for signaling. Crucial regulator in innate immunity to bacterial pathogens (By similarity).
      
 0.799
Il17rd
Interleukin 17 receptor D.
   
 0.793
Il17d
Interleukin 17D.
      
 0.773
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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