STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100910942Serine protease inhibitor Kazal-type 6-like. (105 aa)    
Predicted Functional Partners:
Spink14-2
Serine protease inhibitor Kazal-type 14; May be a serine protease inhibitor.
   
  
 0.741
Spink13
Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction.
   
  
 0.682
Klk14
Kallikrein-related-peptidase 14; Belongs to the peptidase S1 family.
    
 
 0.677
Klk13
Kallikrein-related-peptidase 13; Belongs to the peptidase S1 family.
   
 
 0.652
ENSRNOP00000067273
Kallikrein 1.
   
 
 0.589
Klk15
Kallikrein-15-like; Belongs to the peptidase S1 family.
   
 
 0.587
Klk1c12
Glandular kallikrein-12, submandibular/renal; Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
    
 
 0.563
Klk15-2
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 
 0.563
Klk12
Glandular kallikrein-12, submandibular/renal; Belongs to the peptidase S1 family.
    
 
 0.533
Spink8
Similar to Esophagus cancer-related gene-2 protein (ECRG-2) (Predicted), isoform CRA_a.
      
 0.522
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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