node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Myh6 | Myl1 | ENSRNOP00000023301 | ENSRNOP00000017838 | Myosin-6; Muscle contraction. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.938 |
Myh6 | Myl2 | ENSRNOP00000023301 | ENSRNOP00000039707 | Myosin-6; Muscle contraction. | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] | 0.954 |
Myh6 | Myl3 | ENSRNOP00000023301 | ENSRNOP00000028458 | Myosin-6; Muscle contraction. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.990 |
Myh6 | Tnnc1 | ENSRNOP00000023301 | ENSRNOP00000025606 | Myosin-6; Muscle contraction. | Troponin C1, slow skeletal and cardiac type. | 0.870 |
Myh6 | Tnnc2 | ENSRNOP00000023301 | ENSRNOP00000020348 | Myosin-6; Muscle contraction. | Troponin C2, fast skeletal type. | 0.779 |
Myh6 | Tnni1 | ENSRNOP00000023301 | ENSRNOP00000067933 | Myosin-6; Muscle contraction. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.907 |
Myh6 | Tnni2 | ENSRNOP00000023301 | ENSRNOP00000068190 | Myosin-6; Muscle contraction. | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.835 |
Myh6 | Tnnt1 | ENSRNOP00000023301 | ENSRNOP00000038327 | Myosin-6; Muscle contraction. | Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.838 |
Myh6 | Tnnt2 | ENSRNOP00000023301 | ENSRNOP00000069434 | Myosin-6; Muscle contraction. | Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.951 |
Myh6 | Tnnt3 | ENSRNOP00000023301 | ENSRNOP00000049386 | Myosin-6; Muscle contraction. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.754 |
Myl1 | Myh6 | ENSRNOP00000017838 | ENSRNOP00000023301 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Myosin-6; Muscle contraction. | 0.938 |
Myl1 | Myl2 | ENSRNOP00000017838 | ENSRNOP00000039707 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] | 0.912 |
Myl1 | Myl3 | ENSRNOP00000017838 | ENSRNOP00000028458 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.676 |
Myl1 | Tnnc1 | ENSRNOP00000017838 | ENSRNOP00000025606 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin C1, slow skeletal and cardiac type. | 0.710 |
Myl1 | Tnnc2 | ENSRNOP00000017838 | ENSRNOP00000020348 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin C2, fast skeletal type. | 0.945 |
Myl1 | Tnni1 | ENSRNOP00000017838 | ENSRNOP00000067933 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.952 |
Myl1 | Tnni2 | ENSRNOP00000017838 | ENSRNOP00000068190 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.973 |
Myl1 | Tnnt1 | ENSRNOP00000017838 | ENSRNOP00000038327 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.948 |
Myl1 | Tnnt2 | ENSRNOP00000017838 | ENSRNOP00000069434 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.952 |
Myl1 | Tnnt3 | ENSRNOP00000017838 | ENSRNOP00000049386 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.966 |