STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBLBCbl proto-oncogene B. (935 aa)    
Predicted Functional Partners:
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.995
MST1R
Macrophage stimulating 1 receptor.
    
 0.994
ZAP70
Tyrosine-protein kinase.
    
 0.990
GRB2
Growth factor receptor bound protein 2.
    
 0.981
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 0.977
EGFR
Receptor protein-tyrosine kinase.
    
 0.976
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.969
CRK
CRK proto-oncogene, adaptor protein.
    
 0.966
SPRY2
Sprouty RTK signaling antagonist 2.
    
 0.965
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.964
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.