Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMBNAmeloblastin. (423 aa)    
Predicted Functional Partners:
ENAM
Enamelin.
   
  
 0.959
AMTN
Amelotin.
      
 0.951
AHSG
Alpha-2-HS-glycoprotein.
    
 0.894
BGN
Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
    
 
 0.886
TUFT1
Tuftelin 1.
      
 0.882
SPARCL1
SPARC like 1.
      
 0.880
AMEL
Amelogenin; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity); Belongs to the amelogenin family.
    
 
 0.861
MMP20
Matrix metallopeptidase 20.
   
  
 0.795
COL22A1
Collagen type XXII alpha 1 chain.
    
 0.775
PCOLCE
Procollagen C-endopeptidase enhancer.
      
 0.769
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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