STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FARP1FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1048 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 0.780
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
     
 0.764
PLXNA4
Plexin A4.
     
 0.647
NRP1
Neuropilin; Belongs to the neuropilin family.
     
 0.626
RHOF
Ras homolog family member F, filopodia associated.
     
 0.611
BAIAP2L1
BAI1 associated protein 2 like 1.
     
 0.610
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
     
 0.580
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
     
 0.570
FAM169A
Family with sequence similarity 169 member A.
    
  0.563
DSCAM
DS cell adhesion molecule.
     
 0.561
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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