node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DCN | FMOD | ENSCPOP00000032479 | ENSCPOP00000021474 | Decorin; May affect the rate of fibrils formation. | Fibromodulin. | 0.742 |
DCN | LTBP1 | ENSCPOP00000032479 | ENSCPOP00000006323 | Decorin; May affect the rate of fibrils formation. | Latent transforming growth factor beta binding protein 1. | 0.417 |
DCN | TGFB1 | ENSCPOP00000032479 | ENSCPOP00000001098 | Decorin; May affect the rate of fibrils formation. | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] | 0.987 |
DCN | TGFB3 | ENSCPOP00000032479 | ENSCPOP00000027035 | Decorin; May affect the rate of fibrils formation. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.937 |
FMOD | DCN | ENSCPOP00000021474 | ENSCPOP00000032479 | Fibromodulin. | Decorin; May affect the rate of fibrils formation. | 0.742 |
FMOD | TGFB1 | ENSCPOP00000021474 | ENSCPOP00000001098 | Fibromodulin. | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] | 0.949 |
FMOD | TGFB3 | ENSCPOP00000021474 | ENSCPOP00000027035 | Fibromodulin. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.935 |
ITGAV | ITGB6 | ENSCPOP00000013853 | ENSCPOP00000018590 | Integrin subunit alpha V; Belongs to the integrin alpha chain family. | Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). | 0.998 |
ITGAV | ITGB8 | ENSCPOP00000013853 | ENSCPOP00000008181 | Integrin subunit alpha V; Belongs to the integrin alpha chain family. | Integrin beta; Belongs to the integrin beta chain family. | 0.998 |
ITGAV | LTBP1 | ENSCPOP00000013853 | ENSCPOP00000006323 | Integrin subunit alpha V; Belongs to the integrin alpha chain family. | Latent transforming growth factor beta binding protein 1. | 0.666 |
ITGAV | TGFB1 | ENSCPOP00000013853 | ENSCPOP00000001098 | Integrin subunit alpha V; Belongs to the integrin alpha chain family. | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] | 0.990 |
ITGAV | TGFB3 | ENSCPOP00000013853 | ENSCPOP00000027035 | Integrin subunit alpha V; Belongs to the integrin alpha chain family. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.820 |
ITGB6 | ITGAV | ENSCPOP00000018590 | ENSCPOP00000013853 | Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). | Integrin subunit alpha V; Belongs to the integrin alpha chain family. | 0.998 |
ITGB6 | ITGB8 | ENSCPOP00000018590 | ENSCPOP00000008181 | Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). | Integrin beta; Belongs to the integrin beta chain family. | 0.785 |
ITGB6 | LTBP1 | ENSCPOP00000018590 | ENSCPOP00000006323 | Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). | Latent transforming growth factor beta binding protein 1. | 0.640 |
ITGB6 | TGFB1 | ENSCPOP00000018590 | ENSCPOP00000001098 | Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] | 0.975 |
ITGB6 | TGFB3 | ENSCPOP00000018590 | ENSCPOP00000027035 | Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.745 |
ITGB8 | ITGAV | ENSCPOP00000008181 | ENSCPOP00000013853 | Integrin beta; Belongs to the integrin beta chain family. | Integrin subunit alpha V; Belongs to the integrin alpha chain family. | 0.998 |
ITGB8 | ITGB6 | ENSCPOP00000008181 | ENSCPOP00000018590 | Integrin beta; Belongs to the integrin beta chain family. | Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). | 0.785 |
ITGB8 | LTBP1 | ENSCPOP00000008181 | ENSCPOP00000006323 | Integrin beta; Belongs to the integrin beta chain family. | Latent transforming growth factor beta binding protein 1. | 0.630 |