CD46 protein (Cavia porcellus) - STRING interaction network

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CD46

Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (387 aa)

Predicted Functional Partners:

Cfi

0.986

C3

0.924

H0W7A0_CAVPO

0.924

LOC100728345

0.924

MSN

0.924

DSG2

0.918

Cfh

0.900

JAG1

0.867

PARK7

0.772

MAN2B2

0.769

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3	CD46	ENSCPOP00000018087	ENSCPOP00000001183	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	0.924
C3	Cfh	ENSCPOP00000018087	ENSCPOP00000005165	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Uncharacterized protein.	0.924
C3	Cfi	ENSCPOP00000018087	ENSCPOP00000003800	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.991
C3	LOC100728345	ENSCPOP00000018087	ENSCPOP00000022343	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Anaphylatoxin-like domain-containing protein.	0.900
CD46	C3	ENSCPOP00000001183	ENSCPOP00000018087	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	0.924
CD46	Cfh	ENSCPOP00000001183	ENSCPOP00000005165	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Uncharacterized protein.	0.900
CD46	Cfi	ENSCPOP00000001183	ENSCPOP00000003800	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.986
CD46	DSG2	ENSCPOP00000001183	ENSCPOP00000017107	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Desmoglein 2.	0.918
CD46	H0W7A0_CAVPO	ENSCPOP00000001183	ENSCPOP00000018854	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	NTR domain-containing protein.	0.924
CD46	JAG1	ENSCPOP00000001183	ENSCPOP00000032076	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.867
CD46	LOC100728345	ENSCPOP00000001183	ENSCPOP00000022343	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Anaphylatoxin-like domain-containing protein.	0.924
CD46	MAN2B2	ENSCPOP00000001183	ENSCPOP00000006878	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Alpha-mannosidase.	0.769
CD46	MSN	ENSCPOP00000001183	ENSCPOP00000031240	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Moesin.	0.924
CD46	PARK7	ENSCPOP00000001183	ENSCPOP00000006176	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Parkinsonism associated deglycase.	0.772
Cfh	C3	ENSCPOP00000005165	ENSCPOP00000018087	Uncharacterized protein.	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	0.924
Cfh	CD46	ENSCPOP00000005165	ENSCPOP00000001183	Uncharacterized protein.	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	0.900
Cfh	Cfi	ENSCPOP00000005165	ENSCPOP00000003800	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.847
Cfi	C3	ENSCPOP00000003800	ENSCPOP00000018087	Uncharacterized protein; Belongs to the peptidase S1 family.	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	0.991
Cfi	CD46	ENSCPOP00000003800	ENSCPOP00000001183	Uncharacterized protein; Belongs to the peptidase S1 family.	Membrane cofactor protein; May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	0.986
Cfi	Cfh	ENSCPOP00000003800	ENSCPOP00000005165	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.847

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