PITRM1 protein (Cavia porcellus) - STRING interaction network

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Score

PITRM1

Pitrilysin metallopeptidase 1. (1032 aa)

Predicted Functional Partners:

APP

0.959

APLP2

0.789

ATF6

0.697

ATF6B

0.697

Pdha1

0.664

H0W5C1_CAVPO

0.664

APLP1

0.663

PDHB

0.662

ATP5F1B

0.661

MIPEP

0.658

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLP1	APLP2	ENSCPOP00000006037	ENSCPOP00000011030	Amyloid beta precursor like protein 1.	Amyloid beta precursor like protein 2.	0.487
APLP1	APP	ENSCPOP00000006037	ENSCPOP00000020780	Amyloid beta precursor like protein 1.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.580
APLP1	PITRM1	ENSCPOP00000006037	ENSCPOP00000001299	Amyloid beta precursor like protein 1.	Pitrilysin metallopeptidase 1.	0.663
APLP2	APLP1	ENSCPOP00000011030	ENSCPOP00000006037	Amyloid beta precursor like protein 2.	Amyloid beta precursor like protein 1.	0.487
APLP2	APP	ENSCPOP00000011030	ENSCPOP00000020780	Amyloid beta precursor like protein 2.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.743
APLP2	PITRM1	ENSCPOP00000011030	ENSCPOP00000001299	Amyloid beta precursor like protein 2.	Pitrilysin metallopeptidase 1.	0.789
APP	APLP1	ENSCPOP00000020780	ENSCPOP00000006037	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Amyloid beta precursor like protein 1.	0.580
APP	APLP2	ENSCPOP00000020780	ENSCPOP00000011030	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Amyloid beta precursor like protein 2.	0.743
APP	PITRM1	ENSCPOP00000020780	ENSCPOP00000001299	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Pitrilysin metallopeptidase 1.	0.959
ATF6	ATF6B	ENSCPOP00000009272	ENSCPOP00000026887	Activating transcription factor 6.	Activating transcription factor 6 beta.	0.939
ATF6	PITRM1	ENSCPOP00000009272	ENSCPOP00000001299	Activating transcription factor 6.	Pitrilysin metallopeptidase 1.	0.697
ATF6B	ATF6	ENSCPOP00000026887	ENSCPOP00000009272	Activating transcription factor 6 beta.	Activating transcription factor 6.	0.939
ATF6B	PITRM1	ENSCPOP00000026887	ENSCPOP00000001299	Activating transcription factor 6 beta.	Pitrilysin metallopeptidase 1.	0.697
ATP5F1B	H0W5C1_CAVPO	ENSCPOP00000016071	ENSCPOP00000018173	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.749
ATP5F1B	PDHB	ENSCPOP00000016071	ENSCPOP00000006048	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.713
ATP5F1B	PITRM1	ENSCPOP00000016071	ENSCPOP00000001299	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Pitrilysin metallopeptidase 1.	0.661
ATP5F1B	Pdha1	ENSCPOP00000016071	ENSCPOP00000008332	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.749
H0W5C1_CAVPO	ATP5F1B	ENSCPOP00000018173	ENSCPOP00000016071	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.749
H0W5C1_CAVPO	PDHB	ENSCPOP00000018173	ENSCPOP00000006048	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.999
H0W5C1_CAVPO	PITRM1	ENSCPOP00000018173	ENSCPOP00000001299	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pitrilysin metallopeptidase 1.	0.664