Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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Score
MAP4K2Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (819 aa)    
Predicted Functional Partners:
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.928
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
   
 
 0.807
LATS1
Large tumor suppressor kinase 1.
    
 
 0.793
H0VB67_CAVPO
Phosphatidylinositol 3-kinase catalytic subunit type 3.
      
 0.620
CACNG7
Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
     
 0.619
CRKL
CRK like proto-oncogene, adaptor protein.
    
 
 0.599
GRB2
Growth factor receptor bound protein 2.
    
 
 0.592
LCP2
Lymphocyte cytosolic protein 2.
    
 
 0.579
CRK
CRK proto-oncogene, adaptor protein.
    
 
 0.578
NCK1
Cytoplasmic protein.
    
 
 0.574
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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