STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GGCXGamma-glutamyl carboxylase. (754 aa)    
Predicted Functional Partners:
VKORC1
Vitamin K epoxide reductase complex subunit 1.
   
 
 0.962
NQO1
NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family.
     
 0.941
SUOX
Sulfite oxidase.
     
 0.894
Vkorc1l1
VKc domain-containing protein.
   
 
 0.886
PROS1
Protein S.
     
 0.859
F2
Coagulation factor II, thrombin; Belongs to the peptidase S1 family.
    
 0.858
F9
Coagulation factor IX; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
    
 0.836
F7
Coagulation factor VII.
    
 0.826
BGLAP
Osteocalcin; Binds strongly to apatite and calcium.
     
 0.820
NQO2
N-ribosyldihydronicotinamide:quinone reductase 2.
     
 0.778
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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