STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSAPSaposin-C; Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin- C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. (536 aa)    
Predicted Functional Partners:
GPR37L1
G protein-coupled receptor 37 like 1.
     
 0.932
GALC
Galactosylceramidase.
    
 
 0.918
GPR37
G protein-coupled receptor 37.
     
 0.896
GBA
Glucosylceramidase.
   
 0.864
LAMP1
Lysosomal associated membrane protein 1.
   
  
 0.768
SFTPC
Surfactant protein C.
   
 
 0.766
TMEM130
Transmembrane protein 130.
   
 0.756
CHID1
Chitinase domain containing 1; Belongs to the glycosyl hydrolase 18 family.
     
 0.723
Ctsd
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.689
SORT1
Sortilin.
    
 
 0.682
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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