Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EEDEmbryonic ectoderm development. (417 aa)    
Predicted Functional Partners:
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
 0.999
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
   
 0.999
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.999
JARID2
Jumonji and AT-rich interaction domain containing 2.
    
 0.996
AEBP2
AE binding protein 2.
    
 0.995
PHF19
PHD finger protein 19.
   
 0.992
RNF2
Ring finger protein 2.
    
 0.991
PHF1
PHD finger protein 1.
   
 0.990
MTF2
Metal response element binding transcription factor 2.
   
 0.985
ENSCPOP00000021738
RING-type domain-containing protein.
    
 0.981
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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