Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
INKA2Inka box actin regulator 2. (300 aa)    
Predicted Functional Partners:
KCNIP3
Potassium voltage-gated channel interacting protein 3.
      
 0.650
INKA1
Inka box actin regulator 1.
      
 0.516
PHLDA3
Pleckstrin homology like domain family A member 3.
      
 0.491
PAK4
Non-specific serine/threonine protein kinase.
    
 
 0.485
ENSCPOP00000024144
Protein kinase domain-containing protein.
    
 
 0.485
VASH2
Vasohibin 2.
      
 0.481
GNGT2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.473
LZTS2
Leucine zipper tumor suppressor 2.
      
 0.471
RASSF7
Ras association domain family member 7.
      
 0.461
BUD13
BUD13 homolog.
      
 0.451
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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