node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALOX5 | CYP2E1 | ENSCPOP00000021944 | ENSCPOP00000024284 | Arachidonate 5-lipoxygenase. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.916 |
ALOX5 | LOC100716044 | ENSCPOP00000021944 | ENSCPOP00000008690 | Arachidonate 5-lipoxygenase. | Cytochrome P450 2C-like protein; Belongs to the cytochrome P450 family. | 0.916 |
ALOX5 | PLA2G4A | ENSCPOP00000021944 | ENSCPOP00000022933 | Arachidonate 5-lipoxygenase. | Phospholipase A2. | 0.916 |
ALOX5 | PTGS1 | ENSCPOP00000021944 | ENSCPOP00000006637 | Arachidonate 5-lipoxygenase. | Prostaglandin-endoperoxide synthase 1. | 0.919 |
ALOX5 | PTGS2 | ENSCPOP00000021944 | ENSCPOP00000001794 | Arachidonate 5-lipoxygenase. | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] | 0.919 |
CYP2E1 | ALOX5 | ENSCPOP00000024284 | ENSCPOP00000021944 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | Arachidonate 5-lipoxygenase. | 0.916 |
CYP2E1 | HPGDS | ENSCPOP00000024284 | ENSCPOP00000019270 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | Hematopoietic prostaglandin D synthase. | 0.929 |
CYP2E1 | LOC100716044 | ENSCPOP00000024284 | ENSCPOP00000008690 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 2C-like protein; Belongs to the cytochrome P450 family. | 0.916 |
CYP2E1 | PLA2G4A | ENSCPOP00000024284 | ENSCPOP00000022933 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | Phospholipase A2. | 0.915 |
CYP2E1 | PTGS1 | ENSCPOP00000024284 | ENSCPOP00000006637 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | Prostaglandin-endoperoxide synthase 1. | 0.913 |
CYP2E1 | PTGS2 | ENSCPOP00000024284 | ENSCPOP00000001794 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] | 0.919 |
HPGDS | CYP2E1 | ENSCPOP00000019270 | ENSCPOP00000024284 | Hematopoietic prostaglandin D synthase. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.929 |
HPGDS | LOC100716044 | ENSCPOP00000019270 | ENSCPOP00000008690 | Hematopoietic prostaglandin D synthase. | Cytochrome P450 2C-like protein; Belongs to the cytochrome P450 family. | 0.809 |
HPGDS | PTGES | ENSCPOP00000019270 | ENSCPOP00000024536 | Hematopoietic prostaglandin D synthase. | Prostaglandin E synthase. | 0.931 |
HPGDS | PTGES2 | ENSCPOP00000019270 | ENSCPOP00000026610 | Hematopoietic prostaglandin D synthase. | Prostaglandin E synthase 2; Belongs to the GST superfamily. | 0.934 |
HPGDS | PTGES3 | ENSCPOP00000019270 | ENSCPOP00000029406 | Hematopoietic prostaglandin D synthase. | Prostaglandin E synthase 3. | 0.928 |
HPGDS | PTGIS | ENSCPOP00000019270 | ENSCPOP00000028411 | Hematopoietic prostaglandin D synthase. | Prostaglandin I2 synthase; Belongs to the cytochrome P450 family. | 0.933 |
HPGDS | PTGS1 | ENSCPOP00000019270 | ENSCPOP00000006637 | Hematopoietic prostaglandin D synthase. | Prostaglandin-endoperoxide synthase 1. | 0.943 |
HPGDS | PTGS2 | ENSCPOP00000019270 | ENSCPOP00000001794 | Hematopoietic prostaglandin D synthase. | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] | 0.929 |
LOC100716044 | ALOX5 | ENSCPOP00000008690 | ENSCPOP00000021944 | Cytochrome P450 2C-like protein; Belongs to the cytochrome P450 family. | Arachidonate 5-lipoxygenase. | 0.916 |