CD19 protein (Cavia porcellus) - STRING interaction network

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CD19

B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...] (536 aa)

Predicted Functional Partners:

CD81

0.998

LYN

0.996

CD79A

0.996

CR2

0.995

PIK3R1

0.992

VAV3

0.991

VAV2

0.991

PIK3CA

0.974

PIK3CD

0.972

CD79B

0.972

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD19	CD79A	ENSCPOP00000001807	ENSCPOP00000010695	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	CD79a molecule.	0.996
CD19	CD79B	ENSCPOP00000001807	ENSCPOP00000032365	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	CD79b molecule.	0.972
CD19	CD81	ENSCPOP00000001807	ENSCPOP00000009196	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	Tetraspanin.	0.998
CD19	CR2	ENSCPOP00000001807	ENSCPOP00000025900	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	Complement C3d receptor 2.	0.995
CD19	LYN	ENSCPOP00000001807	ENSCPOP00000010517	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	Tyrosine-protein kinase.	0.996
CD19	PIK3CA	ENSCPOP00000001807	ENSCPOP00000005920	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family.	0.974
CD19	PIK3CD	ENSCPOP00000001807	ENSCPOP00000011659	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.972
CD19	PIK3R1	ENSCPOP00000001807	ENSCPOP00000007043	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	Phosphoinositide-3-kinase regulatory subunit 1.	0.992
CD19	VAV2	ENSCPOP00000001807	ENSCPOP00000023702	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	Vav guanine nucleotide exchange factor 2.	0.991
CD19	VAV3	ENSCPOP00000001807	ENSCPOP00000000599	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	Vav guanine nucleotide exchange factor 3.	0.991
CD79A	CD19	ENSCPOP00000010695	ENSCPOP00000001807	CD79a molecule.	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	0.996
CD79A	CD79B	ENSCPOP00000010695	ENSCPOP00000032365	CD79a molecule.	CD79b molecule.	0.999
CD79A	CR2	ENSCPOP00000010695	ENSCPOP00000025900	CD79a molecule.	Complement C3d receptor 2.	0.612
CD79A	LYN	ENSCPOP00000010695	ENSCPOP00000010517	CD79a molecule.	Tyrosine-protein kinase.	0.995
CD79A	VAV2	ENSCPOP00000010695	ENSCPOP00000023702	CD79a molecule.	Vav guanine nucleotide exchange factor 2.	0.742
CD79A	VAV3	ENSCPOP00000010695	ENSCPOP00000000599	CD79a molecule.	Vav guanine nucleotide exchange factor 3.	0.741
CD79B	CD19	ENSCPOP00000032365	ENSCPOP00000001807	CD79b molecule.	B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]	0.972
CD79B	CD79A	ENSCPOP00000032365	ENSCPOP00000010695	CD79b molecule.	CD79a molecule.	0.999
CD79B	CR2	ENSCPOP00000032365	ENSCPOP00000025900	CD79b molecule.	Complement C3d receptor 2.	0.493
CD79B	LYN	ENSCPOP00000032365	ENSCPOP00000010517	CD79b molecule.	Tyrosine-protein kinase.	0.989

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