STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)    
Predicted Functional Partners:
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
   
 0.962
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.959
GALC
Galactosylceramidase.
     
 0.959
PLPP2
Phospholipid phosphatase 2.
     
 0.959
ACER2
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.959
SGMS1
Sphingomyelin synthase 1.
     
 0.957
SGMS2
Sphingomyelin synthase 2.
     
 0.957
SMPD4
Sphingomyelin phosphodiesterase 4.
     
 0.956
GBA
Glucosylceramidase.
   
 
 0.947
ASAH2
Neutral ceramidase.
     
 0.935
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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