STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100713317Ig-like domain-containing protein; Belongs to the MHC class I family. (363 aa)    
Predicted Functional Partners:
CD8A
CD8 alpha.
    
 0.957
ENSCPOP00000024109
DUF1968 domain-containing protein.
    
  0.943
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
   
 0.913
KLRD1
Killer cell lectin like receptor D1.
    
 0.906
RPA2
Replication protein A2.
   
 0.898
TAPBP
TAP binding protein.
 
 
 0.895
H0VA20_CAVPO
Ig-like domain-containing protein.
    
 0.857
PDIA3
Protein disulfide-isomerase.
    
 0.841
Cd8b
CD8 beta.
    
  0.837
CALR
Calreticulin.
    
 0.836
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.