STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1856 aa)    
Predicted Functional Partners:
RXFP2
Relaxin family peptide receptor 2.
   
 0.758
Rxfp1
Relaxin/insulin-like family peptide receptor 1.
   
 0.758
ENSCPOP00000026160
Uncharacterized protein.
   
 0.758
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.758
FREM1
FRAS1 related extracellular matrix 1.
    
  0.747
FREM3
FRAS1 related extracellular matrix 3.
    
  0.747
GPIHBP1
Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1.
     
 0.698
SCG5
Secretogranin V.
   
 
 0.689
TGFB1
Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]
    
 0.613
BSND
Barttin CLCNK type accessory beta subunit.
      
 0.602
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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