STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (488 aa)    
Predicted Functional Partners:
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
 
   
 0.716
PTCH2
Patched 2.
     
 0.681
PTCH1
Patched 1.
     
 0.679
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
 
   
 0.588
H0W3X9_CAVPO
Uncharacterized protein.
    
  0.569
ENSCPOP00000024297
Uncharacterized protein.
    
  0.569
SH2D3C
SH2 domain containing 3C.
      
 0.557
PDGFRB
Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
      
 0.531
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
 
   
 0.496
ZBTB16
Zinc finger and BTB domain containing 16.
      
 0.480
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.