STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HHATHedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family. (494 aa)    
Predicted Functional Partners:
PALB2
Partner and localizer of BRCA2.
  
 
 0.945
NDUFAB1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.945
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
  
 0.934
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.786
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.769
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.715
UGDH
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
  
 0.482
HAS3
Hyaluronan synthase 3.
  
 
 0.471
HAS1
Hyaluronan synthase 1.
  
 
 0.471
HAS2
Hyaluronan synthase 2.
  
 
 0.471
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.