STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1GProtein phosphatase, Mg2+/Mn2+ dependent 1G. (540 aa)    
Predicted Functional Partners:
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
   
 0.763
USP40
Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family.
   
 0.648
MTFMT
Mitochondrial methionyl-tRNA formyltransferase.
  
   0.633
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.611
TRIP12
Thyroid hormone receptor interactor 12.
      
 0.611
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
   
 0.611
PPIL4
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  
 
 0.607
SF3A2
Splicing factor 3a subunit 2.
   
  
 0.594
SIRT7
Sirtuin 7.
   
 
 0.589
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.589
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.